Centers for Disease Control and Prevention.

Serious adverse events after measles-mumps-rubella vaccination during a fourteen-year prospective follow-up. Narrative [corrected] review: bisphosphonates and osteonecrosis of the jaws. Dermatologic emergencies. This website also contains material copyrighted by 3rd parties. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA4MDc3Mi1vdmVydmlldw== Generalized or multifocal involvement of the gingival tissues may be observed, with marked erythema and erosion of the superficial gingiva, a pattern that has been called desquamative gingivitis. Rosenblatt AE, Mockenhaupt M, Ruggiero SL, Dodson TB, Fantasia J, Goodday R, Aghaloo T, Mehrotra B, et al. Odom RB, James WD, Berger TG, eds. A skin biopsy may be required in atypical cases but is more useful for ruling out other processes.Most cases of EM are self-limited and resolve within 4 weeks without treatment.

Atypical erythema multiforme—a marker of malignancy? Please confirm that you would like to log out of Medscape. All rights Reserved. Holland KE, et al. These include barbiturates, beta-blockers, dapsone, NSAIDs, phenazone derivatives, thiazide derivatives, phenolphthalein, sulfonamides, and tetracyclines. Davis MD. Aspirin is often used by patients seeking relief from dental pain. Other patients whose mouths appear to be clinically dry may have no complaints. Autoimmune bullous dermatoses: a review. Rash is a common chief complaint for patients presenting to their physician, especially within the pediatric field. In lower epidermal layers, this viral polymerase protein is synthesized, resulting in activation of HSV-specific T-cells and an inflammatory response.Diagnosis of EM is clinical in most cases.
Immunologic hepatitis 7.
et al. The clinical patterns of adverse drug reactions of the oral cavity include xerostomia, swelling, nonspecific ulceration, vesiculobullous or ulcerative mucositis that mimics other disease states, nonspecific vesiculoulcerative mucositis, pigmentation, gingival enlargement, and medication-related osteonecrosis of the jaws.Agents include antidepressants and antipsychotics, antihypertensives, antihistamines, anticholinergics, and decongestants.Agents include penicillins, aspirin, sulfa drugs, and ACE inhibitors.Agents include antineoplastics (methotrexate, 5-fluorouracil, doxorubicin, and melphalan); barbiturates; dapsone; phenazone derivatives; phenolphthalein; sulfonamides; tetracyclines; NSAIDs (indomethacin, salicylates, gold salts, naproxen); meprobamate; methyldopa; penicillamine; phenylbutazone; propranolol; spironolactone; thiazides; tolbutamide; alendronate; captopril; phenytoin; MTOR inhibitors (sirolimus, temsirolimus, everolimus, ridaforolimus); and (by direct contact) compounds containing aspirin, hydrogen peroxide, or phenol.Reactions may include lichen planus–like, erythema multiforme (EM)–like, pemphigoid-like, Antibiotics (aminosalicylate sodium, isoniazid, rifampin, ethambutol, pyrazinamide, streptomycin, tetracyclines)Anticonvulsants (carbamazepine, oxcarbazepine, phenytoin, valproate)Antidiabetics (chlorpropamide, glipizide, insulin, tolbutamide)Antihistamines (cimetidine, cinnarizine, triprolidine)Antihypercholesterolemia (pravastatin, simvastatin, fluvastatin, lovastatin)Antihypertensives (atenolol, captopril, chlorothiazide, enalapril, furosemide, hydrochlorothiazide, methyldopa, metoprolol, oxprenolol, propranolol, spironolactone)Antimalarials (chloroquine, hydroxychloroquine, pyrimethamine, quinacrine, quinidine)Antineoplastics (imatinib, rituximab, nivolumab, letrozole)Chemotherapeutics (dactinomycin, imatinib, palladium)Immunomodulators (dapsone, gold salts, interferon-alfa, levamisole, penicillamine, infliximab, adalimumab, etanercept, abatacept, obinutuzumab, rituximab)NSAIDs (acetylsalicylic acid, para-aminosalicylic acid, diflunisal, ibuprofen, indomethacin, naproxen, rofecoxib, sulindac)Psychiatrics (benzodiazepines, tricyclic antidepressants, levopromazine, lithium, lorazepam, phenothiazines, pyritinol)Erythema multiforme (EM)–like agents may include the following:Antibiotics (antimalarials, penicillins, sulfonamides, tetracyclines)Antirheumatics (penicillamine, ibuprofen, phenacetin)Cardiovascular drugs (furosemide, captopril, clonidine)Agents include amiodarone; antimalarials (chloroquine, hydrochloroquine, hydroxychloroquine, quinacrine, quinidine); busulfan; clofazimine; cyclophosphamide; estrogen; imatinib; ketoconazole; minocycline; phenolphthalein; chlorpromazine; and zidovudine.Agents include calcium channel blockers (amlodipine, bepridil, diltiazem, felodipine, isradipine, nicardipine, nifedipine, nimodipine, nisoldipine, nitrendipine, oxidipine, verapamil); other dihydropyridines (bleomycin); cyclosporine; phenytoin; and sodium valproate.Xerostomia, or dry mouth, is the most common adverse drug-related effect in the oral cavity.

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