chronic lithium nephropathy

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1American Journal of Physiology-Renal Physiology, Vol. In 8 patients, the duration of lithium therapy was 4 to 20 years (average, 14.5 years); in 2 patients, the precise duration of therapy was not available, although each was described as receiving “long‐term” therapy. Division of Ultrasound Services, Department of Imaging, Dana-Farber Cancer Institute, Boston, Massachusetts USADepartment of Radiology, Brigham and Women's Hospital, Boston, Massachusetts USADepartment of Radiology, Brigham and Women's Hospital, Boston, Massachusetts USADepartment of Radiology, Harvard Medical School, Boston, Massachusetts USADepartment of Radiology, Division of Abdominal Imaging, Georgetown University Hospital, Washington, DC USADivision of Ultrasound Services, Department of Imaging, Dana-Farber Cancer Institute, Boston, Massachusetts USADepartment of Radiology, Brigham and Women's Hospital, Boston, Massachusetts USADepartment of Radiology, Brigham and Women's Hospital, Boston, Massachusetts USADepartment of Radiology, Harvard Medical School, Boston, Massachusetts USADepartment of Radiology, Division of Abdominal Imaging, Georgetown University Hospital, Washington, DC USAPortions of this article were presented in poster form at the 2010 European Congress of Radiology Annual Meeting; March 4–8, 2010; Vienna, Austria.Use the link below to share a full-text version of this article with your friends and colleagues.

Cysts were categorized as microcysts (<2 mm) or macrocysts (>2 mm). 7Journal of the American Society of Nephrology, Vol. The chronic lithium nephrotoxicity picture is dominated by polyuria and evidence of chronic kidney disease. We report a case of a 14-year-old boy who was on lithium … Histopathologic correlation, limited to a single patient, showed many 1‐ to 2‐mm microcysts but, in addition, noted intratubular focal calcification and protein resorption granules.The limitations of this observational series included the method of case collection, the small sample size, and limited pathologic proof. It appears that a well‐performed sonographic examination using high‐frequency transducers, harmonic imaging, and cine clips can detect microcysts at least as well as CT and MRI, and sonography has the distinct advantage of detecting punctate echogenic foci.

Nevertheless, in patients with chronic renal insufficiency and a history of long-term lithium therapy, MR imaging is a noninvasive, accurate diagnostic modality that is able to reveal the presence of characteristic parenchymal microcysts and allow confirmation of the clinical diagnosis of chronic lithium nephropathy. 112 October 2015 | The International Journal of Psychiatry in Medicine, Vol.

302, No. 25, No. 44, No. On MRI, numerous microcysts were visible, but there were no signal voids to suggest calcium deposition. 31, No.

1840, No.

The sonographic examinations were requested for renal conditions in 6 patients and for other reasons in 4. 6 In fact, the main objective, to be shared with the psychiatrist, is to encourage the maintenance of therapy even in the presence of nephropathy. PURPOSE: To evaluate the appearance of lithium nephropathy at magnetic resonance (MR) imaging.

Transverse right renal sonogram with harmonic imaging showing numerous punctate echogenic foci and relatively fewer microcysts. 522 January 2014 | Physiological Reports, Vol.

The group of static images or cine clip showing the most severe involvement was used in all cases as the basis for final categorization. Given that only 10 cases were collected over a 4‐year period from a database of approximately 36,000 abdominal sonographic examinations, this condition is likely a rare occurrence. Only 2 MRI examinations were performed in our patients; the sonograms in each had both visible punctate echogenic foci and microcysts, whereas the MRI examinations showed only microcysts (Differential considerations for multiple renal microcysts include polycystic renal disease and glomerulocystic disease.

With respect to microcysts, 8 of 10 patients (80%) had numerous or many; 1 patient each had several or few.

430 March 2012 | Journal of Geriatric Psychiatry and Neurology, Vol.

By consensus, they formulated the results reported in this series.Two correlative MRI examinations were performed using a GE HDX unit at 1.5 T and running software packages 12 and 15. 520 March 2018 | psychopraxis.

The present series includes 74 patients treated with lithium for a mean period of about 20 years. Cine clips, when available, were used in addition to static images to analyze the number and location for each finding.

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