In most instances, there were no significant differences between theophylline and salbutamol. The absence of an arrhythmogenic interaction between salbutamol and theophylline in our population is similar to the findings of two recent studies in which no clinically important arrhythmias or increased arrhythmia frequency22, I have been getting jittery when using Advair, Prednisone, Theophylline and Ventolin, and my doctor says Atrovent may help instead of Ventolin, so I am wondering what the difference is between … 2 An initial single intravenous dose study was performed to estimate each patient's theophylline kinetics and to identify those patients who would respond to theophylline. chronic airflow obstruction (mean age 65±8 SD, mean FEV Combination therapy produced significantly greater improvement in FEV1, FVC, V50, Raw, and RV than either agent alone.

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3 b). 1993 Jul;104(1):179-84. doi: 10.1378/chest.104.1.179.Nishimura K, Koyama H, Ikeda A, Sugiura N, Kawakatsu K, Izumi T.Chest.

1 The effect of inhaled salbutamol following a maximally effective dose of theophylline given by intravenous infusion was determined in 12 patients with chronic bronchitis.

The bronchodilator effects of 375 mg theophylline orally and 200 μg salbutamol by pressurized aerosol were compared in a randomized, cross‐over, double‐blind trial in fourteen asthmatic patients.Salbutamol produced significantly greater bronchodilatation than theophylline for the initial 30 min (Theophylline demonstrated a longer duration of action than salbutamol, with a significantly greater FEVThere was no significant difference between the total effect of each drug for the 360 min period, as calculated by the areas under the respective FEVPlease check your email for instructions on resetting your password. To read this article in full you will need to make a paymentInappropriate ventilation and hypoxemia as causes of cardiac arrhythmias.Arrhythmia and tachycardia in pulmonary heart disease.Arrhythmias associated with acute respiratory failure in patients with chronic airway obstruction.Cardiac arrhythmias in hospitalized patients with chronic obstructive pulmonary disease.Longterm electrocardiographic monitoring of ambulatory patients with chronic airway obstruction.Arrhythmogenic effects of orally administered bronchodilators.Cardiac dysrhythmias during the treatment of acute asthma.Cardiopulmonary effects of terbutaline and a bronchodilator combination in chronic obstructive pulmonary disease.Cardiac arrhythmias due to oral aminophylline in patients with chronic obstructive pulmonary disease.Cardiac arrhythmias in patients with mild-to-moderate obstructive lung disease.Theophylline and aerosolized terbutaline in the treatment of bronchial asthma: double-blind comparison of optimal doses.Relationship between serum theophylline levels and pulmonary function before and after inhaled beta-agonist in “stable” asthmatics.Responses to large doses of salbutamol and theophylline in patients with chronic obstructive pulmonary diseases.High speed analysis of ventricular arrhythmias from 24-hour recordings.Reliability of quantitative analysis of ambulatory ECG tape recordings.Role of ambulatory electrocardiographic monitoring: Accuracy of quantitative analysis system.A new method for evaluating antiarrhythmic drug efficacy.Antiarrhythmic efficacy of encainide and quinidine: validation of a model for drug assessment.Concomitant bitolterol mesylate aerosol and theophylline for asthma therapy, with 24 hr electrocardiographic monitoring.Cardiac arrhythmias during the combined use of beta-adrenergic agonist drugs and theophylline.Has the change to beta agents combined with oral theophylline increased cases of fatal asthma?.© 1987 The American College of Chest Physicians. The difference between the two means approached statistical significance (p = 0.06). Caffo AL. Elsevier Science Children treated with the theophylline and salbutamol combination had higher pulse rates, lower peak flow measurements, and depressed blood theophylline levels.

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