The more serious risk of thromboembolism, according to a later study by two of the same researchers, is greatly reduced by the use of transdermal estrogen therapy in patients over the age of 40, in whom “a high incidence of venous thromboembolism was observed with oral oestrogens.” (van Kesteren et al 1997) A 1998 study in which estrogen was administered by injection or orally reported incidence of thromboembolic events as “negligible” (Schlatterer et al).In a 1989 retrospective study, combined treatment with estrogen and cyproterone acetate was associated with increases in hyperprolactinemia (Asscheman, Gooren, & Eklund).

Yay! To avoid some confusion, the abbreviation for micrograms is not used in these tables. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. However, Gn-RH analogs are more expensive.

A case study comparing trans women who had been on estrogen for less than two years with those who’d been on it for longer found increased bone density in the women who’d been on estrogen longer (Reutrakul et al 1998).In a 1989 retrospective study, combined treatment with estrogen and cyproterone acetate [an androgen-blocker] was associated with increases in depressive mood changes (Asscheman, Gooren, & Eklund). 17ß estradiol.

If you have an article you like, or a worry to talk about, or you just want to vent a bit about trans life, then we're here!Press J to jump to the feed.

Of those, four (19%) reported hormone regimens that were within the guidelines given by Asscheman and Gooren or Lawrence.Of those who were not within the guidelines, the differences ranged from the possibly ineffective to the potentially dangerous. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. It’s a fact that some transsexuals choose—usually because it’s the only option available to them—to self-prescribe hormones and/or androgen-blocking drugs. She was losing bone mass at the rate of 5% per year while taking androgen-blockers without also taking estrogen (Hierl et al 1999). At least my voice won’t break this time – and I won’t start growing a shit beard.

For reference, I got these pills from Howard Brown.Initially they had me on 200mg Spiro and 2mg Estradiol. Taking more than your prescribed dose also greatly increases your health risks.

It is recommended that MTFs take bot… The study linked elevated prolactin levels with higher estrogen dosage as well as with increased age, and suggested using the lowest effective dosages of estrogen (Asscheman et al 1988). Don't take estrogen orally, however, if you have a personal or family history of venous thrombosis.

Select one or more newsletters to continue. Even after discontinuation of hormone therapy, testicular function might not recover sufficiently to ensure conception.If you want to have biological children, talk to your doctor about freezing your sperm (sperm cryopreservation) before beginning feminizing hormone therapy.Other side effects of estrogen use in trans women include reduced libido, erectile function and ejaculation.

Taking more hormones than the dose you were prescribed is not a good way to try to speed up changes. The evaluation might include:You might also need a mental health evaluation by a provider with expertise in transgender health. If feminizing hormone therapy is started before the changes of male puberty begin, male secondary sex characteristics, such as increased body hair and changes in voice pitch, can be avoided. Your timeline might look as follows:During your first year of feminizing hormone therapy, you'll need to see your doctor approximately every three months for checkups, as well as anytime you make changes to your hormone regimen. Conjugated estrogens in a dose of 2.5 and 5 mg orally per day are clearly associated with an increased risk of thrombosis. (Becerra Fernandez et al 1999) However, the higher levels of cholesterol and triglycerides were still within normal levels (Citkowitz 2001, Isley 2002) and the lower incidence of other factors associated with heart disease, such as elevated plasma tHcy levels (Giltay et al 1998), suggest this is an acceptable risk.Spironolactone use can cause hyperkalemia, an excessive amount of potassium in the blood.

This is individual. Hormone therapy is not typically used in children.Feminizing hormone therapy isn't for all trans women.

Taking a higher dose can actually slow down the changes you want: extra estrogen in the body can be converted to testosterone by an enzyme called aromatase. You should only be using one drug at the recommended dosage from each category.Note that mg is an abbreviation for milligrams, not to be confused with µg, the abbreviation for micrograms. Typically, people who seek feminizing hormone therapy experience distress due to a difference between experienced or expressed gender and sex assigned at birth (gender dysphoria). Changes caused by these medications can be temporary or permanent.

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