Kim P, Louis C, Muralee S, Tampi RR. Recommendations of the 4th Canadian Consensus Conference on the Diagnosis and Treatment of Dementia (CCCDTD4). Cole C, Richards K. Sleep disruption in older adults. Complaints of sleep difficulty are common among the elderly. The relations among caregiver stress, "sundowning" symptoms, and cognitive decline in Alzheimer's disease. Jean-Louis G, Kripke DF, Ancoli-Israel S, et al.
Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women. Up to a third of elderly people in the UK are prescribed sleeping pills because they are affected by insomnia.
Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. Observed over time, a proportion of the elderly population will suffer cognitive decline in any event, and some studies are hampered by the lack of an appropriate control group. Edinger JD, Fins AI, Glenn DM, et al. The tests used to detect POCD vary among studies, making comparison difficult.
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Eszopiclone is a nonbenzodiazepine hypnotic pyrrolopyrazine derivative of the cyclopyrrolone class. Several diverse factors may contribute to sleep disturbances in a large percentage of the elderly population, including retirement, health problems, death of spouse/family members, and changes in circadian rhythm. [Guideline] Nakajima GA, Wenger NS.
Disruptive behavior as a predictor in Alzheimer disease.
Insomnia in the elderly: cause, approach, and treatment. Insomnia symptoms and suicidality in the National Comorbidity Survey - Adolescent Supplement. The orexin neuropeptide signaling system is a central promoter of wakefulness.
It has a short half life (1 hour) and at small doses, it is an effective sleep inducer. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMjkyNDk4LW1lZGljYXRpb24= Shimazaki M, Martin JL.
Vitiello MV, Bliwise DL, Prinz PN. Barry PJ, Gallagher P, Ryan C. Inappropriate prescribing in geriatric patient.
Sleep disorders are commonly underdiagnosed and are a significant source of concern in the geriatric population.
An actigraphic comparison of sleep restriction and sleep hygiene treatments for insomnia in older adults.
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Anderson, P. FDA Approves New Device for Insomnia.
The American Geriatrics Society 2012 Beers Criteria Update Expert Panel.
Diagnosis and Treatment of Chronic Insomnia: A Review. /viewarticle/924134
The majority of BDP users (92%) were women.
Fast Five Quiz: Are You Prepared to Confront Seasonal Affective Disorder?Multiple Sclerosis Prodrome Holds Promise of Earlier DiagnosisSleep Disruption Tied to Energy Homeostasis Gene Variants in HIV PatientsFive Healthy Lifestyle Choices Tied to Dramatic Cut in Dementia RiskNew Data on Birth Defects With Antidepressant Use in PregnancySupplement Plus Probiotic May Improve Depressive Symptoms COVID-19 Tied to Wide Range of Neuropsychiatric ComplicationsProgression of Sleep Disturbances in Early Parkinson’s DiseaseSleep Disruption Tied to Energy Homeostasis Gene Variants in HIV PatientsReduced 'Sleep Pressure' Contributes to Insomnia in AutismShare cases and questions with Physicians on Medscape consult. Sedating antidepressants like trazodone and mirtazapine in low doses are often prescribed at bedtime for insomnia. It is indicated for insomnia characterized by difficulty with sleep onset.
Alessi CA, Yoon EJ, Schnelle JF, et al. Bridging the gap between science and clinical practice. Tariq SH, Pulisetty S. Pharmacotherapy for insomnia.
Sundowning in Dementia: Clinical Relevance, Pathophysiological Determinants, and Therapeutic Approaches.
Medications used for insomnia in this population include antidepressants, nonbenzodiazepines, a melatonin agonist, and herbals.
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Koo BB, Blackwell T, Ancoli-Israel S, Stone KL, Stefanick ML, Redline S. Association of incident cardiovascular disease with periodic limb movements during sleep in older men: outcomes of sleep disorders in older men (MrOS) study. Obstructive sleep apnea syndrome, restless legs syndrome, and insomnia in geriatric patients. Krystal AD, Durrence HH, Scharf M, Jochelson P, Rogowski R, Ludington E, et al.
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The precise mechanism of action is unknown but is believed to be an interaction with the GABA-receptor at binding domains close to or allosterically coupled to benzodiazepine receptors. Barbiturates are effective only for short-term use, losing much of their effectiveness after 2 weeks of administration.
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