Available for Android and iOS devices. FDA pregnancy category B. Select one or more newsletters to continue.

Pregnancy Category B. Tell your doctor if you are pregnant or if you become pregnant while using this medication.

Malaria can increase the risk for adverse pregnancy outcomes, including prematurity, spontaneous abortion, and stillbirth. These data showed that pregnant women who took mefloquine at various doses for both prevention and treatment of malaria did not have an increased risk of teratogenic effects (birth defects) or adverse pregnancy outcomes compared to the background rate in the general population. Pregnancy Category Explanation; All Trimesters: B: Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. Data from published studies in pregnant women have shown no increase in the risk of teratogenic effects or adverse pregnancy outcomes after treatment or prophylaxis with this drug during pregnancy.In 1 study in a few subjects, low levels (3% to 4%) of this drug were excreted into human milk after a dose equal to 250 mg of the free base.Use is considered acceptable; caution is recommended.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.

If travel cannot be avoided, malaria infection is largely preventable with the appropriate antimalarial drugs along with other measures to prevent mosquito bites.To receive email updates about this page, enter your email address:Update: New Recommendations for Mefloquine Use in PregnancyCenters for Disease Control and Prevention. The Centers for Disease Control and Prevention (CDC) now recommends the antimalarial drug mefloquine for pregnant women both as a malaria treatment option and as an option to prevent malaria infection for all trimesters. Previously mefloquine was not recommended for the treatment of malaria in pregnant women. This drug should be used during pregnancy only if clearly needed and the benefit outweighs the risk.Animal studies have revealed evidence of embryotoxicity and teratogenicity.
However, unplanned pregnancy during use of this drug is not an indication for terminating the pregnancy. This drug crosses the placenta and is detectable in fetal circulation. Data from published studies in pregnant women have shown no increase in the risk of teratogenic effects or adverse pregnancy outcomes following Mefloquine treatment or prophylaxis during pregnancy. The change in recommendations is based on the recent Food and Drug Administration (FDA) re-categorization of mefloquine from a pregnancy category C drug to category B, based on their review of the published data on mefloquine use during pregnancy. Mefloquine was more efficacious than sulfadoxine-pyrimethamine in HIV-uninfected women or daily cotrimoxazole prophylaxis in HIV-infected pregnant women for prevention of malaria infection and was associated with lower risk of maternal anaemia, no adverse effects on pregnancy outcomes (such as stillbirths and abortions), and no effects on low birth weight and …
Pregnant women should avoid travel to malaria-endemic areas if possible. Based on studies, the FDA assigns risk categorizes for drugs used in pregnancy which include categories A, B, C, D, and X with categories A and B demonstrating the least risk to the pregnancy.Malaria is a serious, sometimes fatal, mosquito-borne disease.

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