The recruitment began in May 2019 and is expected to complete by June 2021.Berman B, Perez O, Konda S, Kohut B, Viera M, Delgado S, et al. J Pakistan Assoc Dermatol. Advice will be given to patients over the phone, or they will be invited to present to hospital for review for further management.There will be an independent data and safety monitoring committee, including assessors independent of the Department of Women’s and Newborn Health, who will review all data and conduct audits of the trial at intervals to assess the safety and critical efficacy of the intervention, disentangle harms of corticosteroids from surgical complications and accordingly decide whether to continue, modify or stop the clinical trial.An interim analysis will be performed on the primary outcome of keloid formation in patients when enrolling 20 patients, including both the control and intervention groups, by a single statistician who is blinded to allocation and reports the results to the data and safety monitoring committee.If there is a reasonable suspected causal relationship with the intervention, the study researcher who is blinded to the allocations will report to the data and safety monitoring committee, who will in turn report the adverse events to the ethics committee to guarantee the safety of the patients. Br J Plast Surg. Am J Surg. J Am Acad Dermatol.

Those women who meet the inclusion criteria and sign the informed consent form will be randomised to either the intervention or the control group.The authors declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.SPIRIT checklist: recommended items to address in a clinical trial protocol and related documents. The relative and individual benefits of steroid injections are enumerated below: Unlike topical steroids, this method reduces the chances of thinning of the surface skin, also otherwise known as epidermal atrophy. This will prevent the researcher from influencing which participants are assigned to a given intervention group and reporting bias.Through a parallel intervention assignment, the independent researcher will use a computer-Vgenerated random-numbers list to determine group allocation. 2004;17(2):212–8.Niessen F, Spauwen P, Schalkwijk J, Kon M. On the nature of hypertrophic scars and keloids: a review. 1999;69(9):655–9.Sharma S, Bassi R, Gupta A. Comparing quality of life in women after vaginal delivery and cesarean section. 2017;18(3):606.Ogawa R, Akaishi S. Endothelial dysfunction may play a key role in keloid and hypertrophic scar pathogenesis–keloids and hypertrophic scars may be vascular disorders.

The baby will be delivered as normal, and routine wound closure will be performed in accordance with National Institute for Health and Care Excellence (NICE) guidelines as follows: The uterus is closed in two layers followed by closure of the rectus sheath, all using continuous sutures with 1-Vicryl (Johnson & Johnson). The main reason I wish my doctor would have been more conservative with his cortisone is because my flare-ups were all pretty localized around the same two areas: my nose and my chin. My cortisone injection experience started with just that one enormous cyst that sent me running to the nearest dermatologist. Then, I had cystic acne springing up on my chin and nose regularly. Plast Reconstr Surg. What I Wish I'd Known Before I Tried Micro-Needling 2009;9:4.Mousavi SA, Mortazavi F, Chaman R, Khosravi A. To improve the objective validity of the trial and minimise recall bias of patients in the symptom scores, the participants will be shown photographs of the scar both before and one year after the intervention. 1988;19:537.Wang A, Armstrong E, Armstrong A. Corticosteroids and wound healing: clinical considerations in the perioperative period. Only aggregated results will be reported, in which no individual or identifying data will be included.The data will be disposed of 10 years after publication of the results as required by Western Sydney Local Health District (WSLHD) Human Research Ethics Committee (HREC) policy.
The tool has been used in previous studies on perinatal women in Australia, Canada, Chile, England, Germany, Iceland, New Zealand and the USA with reasonable response rates [After the participant has had her caesarean section, the surgeon will complete a questionnaire. How Accepting My Acne Is a Radical Form of Self Love

Salma Hayek’s Facialist Fixed My Hormonal Acne With These Skincare Tips 2013;206(3):410–7.Grumbine N, Dobrowolski C, Bernstein A. Retrospective evaluation of postoperative intralesional steroid injections on wound healing. 2008;61(9):1049–58.Ogawa R. Keloid and hypertrophic scars are the result of chronic inflammation in the reticular dermis.

This 9-year-old boy had a mild right scapular keloid and was treated by fludroxycortide tape (Drenison® tape).

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