IMURAN is usually given as a single daily dose on the day of, and in a minority of cases 1 to 3 days before, transplantation.

1-2 mg/kg PO once daily to maximum daily dose of 150 mg for at least 3-6 months before typical response is observed.

250 mg twice daily, dose may be doubled in severe lower respiratory-tract infections or if pneumonia is suspected. Dosage Modifications Renal impairment.

per dose 250 mg). The dose of IMURAN should not be increased to toxic levels because of threatened … Available for Android and iOS devices. Die Dosierung von Cefuroxim AL 500 Filmtabletten hängt grundsätzlich von den Anweisungen Ihres Arztes sowie … Cefuroxime (Ceftin) is an oral drug used to treat bacterial infections.

Early drug discontinuation may be considered in patients with abnormal CBC results that do not respond to dose reduction (see CLINICAL PHARMACOLOGY, WARNINGS: Cytopenias, and PRECAUTIONS: Laboratory Tests).Because of the risk of increased toxicity, consider alternative therapies for patients who are known to have TPMT or NUDT15 deficiency (see CLINICAL PHARMACOLOGY, WARNINGS: Cytopenias, and PRECAUTIONS: Laboratory Tests).Because of the risk of increased toxicity, dosage reduction is recommended in patients known to have heterozygous deficiency of TPMT or NUDT15. CrCl >30 mL/min: No adjustment necessary; CrCl 10-30 mL/min: Administer dose q24hr; CrCl ; 10 mL/min: Administer dose q48hr Dosing … Lower dosage (100 mg/day) is … per dose 125 mg). Cefuroxim wird unter anderem bei Infektionen der Atem- und Harnwege sowie bei Versagen einer Antibiotika …

The initial dose is usually 3 to 5 mg/kg daily, beginning at the time of transplant.

The dose of IMURAN should not be increased to toxic levels because of threatened rejection.

Patients who are heterozygous for both TPMT and NUDT15 deficiency may require more substantial dosage reductions (see CLINICAL PHARMACOLOGY, WARNINGS: Cytopenias, and PRECAUTIONS: Laboratory Tests).Procedures for proper handling and disposal of this immunosuppressive antimetabolite drug should be considered. Applies to the following strengths: 7.5 g; 750 mg; 1.5 g; 250 mg; 500 mg; 125 mg; 125 mg/5 mL; 750 mg/50 mL-5%; 1.5 g/50 mL-5%; 250 mg/5 mLOral (tablets): 250 or 500 mg orally every 12 hoursOral (tablets): 250 or 500 mg orally every 12 hours for 10 daysUncomplicated infections: 750 mg IV or IM every 8 hoursOral (tablets): 250 to 500 mg orally every 12 hours for 10 daysOral (tablets): 250 to 500 mg orally every 12 hours for 10 daysLife-threatening infections or infections due to less susceptible organisms: 1.5 g IV every 6 hoursLife-threatening infections or infections due to less susceptible organisms: 1.5 g IV every 6 hoursSIS and IDSA Recommendations: 1.5 g IV every 8 hoursSIS and IDSA Recommendations: 1.5 g IV every 8 hoursSIS and IDSA Recommendations: 1.5 g IV every 8 hours3 months or older: 50 to 100 mg/kg/day IV or IM in equally divided doses every 6 to 8 hours3 months or older: 50 to 100 mg/kg/day IV in equally divided doses every 6 to 8 hours3 months or older: 200 to 240 mg/kg/day IV in divided doses every 6 to 8 hoursSIS and IDSA Recommendations: 150 mg/kg/day IV in divided doses every 6 to 8 hoursSafety and efficacy have not been established in patients younger than 3 months.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.

10 mg/kg twice daily (max. For Child 2–11 years. Select one or more newsletters to continue. Dosing considerations. Maintenance therapy should be at the lowest effective dose, and the dose given can be lowered decrementally with changes of 0.5 mg/kg or approximately 25 mg daily every 4 weeks while other therapy is kept constant.

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