Patients with renal and/or liver disease may be at greater risk for adverse effects from bisoprolol due to decreased drug clearance.

In patients with pheochromocytoma, an alpha-blocking agent should be initiated prior to the use of any beta-blocking agent. If dosage must be increased, dividing the dose should be considered to achieve lower peak blood levels. Applies to: HyperthyroidismWhen beta-adrenergic receptor blocking agents (aka beta-blockers) are used to alleviate symptoms of hyperthyroidism such as tachycardia, anxiety, tremor and heat intolerance, abrupt withdrawal can exacerbate thyrotoxicosis or precipitate a thyroid storm. Major Potential Hazard, High plausibility. To provide accurate information on drug-herb interactions healthcare providers must account for product verification, dosage, medicinal plant species, and plant part used. The use of beta-adrenergic receptor blocking agents (aka beta-blockers) should be administered cautiously in these patients.Moderate Potential Hazard, Moderate plausibility. Applies to: Diabetes MellitusBeta-adrenergic receptor blocking agents (aka beta-blockers) may mask symptoms of hypoglycemia such as tremors, tachycardia and blood pressure changes. 2014 Jul;7(2):83-95. doi: 10.2174/1872312808666140129123210.Clin Pharmacokinet. There are 3 alcohol/food interactions with Zebeta (bisoprolol) The hemodynamic status should be closely monitored before and after the dose.Major Potential Hazard, High plausibility. This information does not contain all possible interactions or adverse effects. The frequency and/or severity of attacks may be increased during beta-blocker therapy.

The study is created by eHealthMe based on reports of 3 people who take the same drugs from the FDA, and is updated regularly. Applies to: Myoneural DisorderBeta-adrenergic receptor blocking agents (aka beta-blockers) may potentiate muscle weakness consistent with certain myasthenic symptoms such as diplopia, ptosis, and generalized weakness.

Epub 2006 Nov 3.Modarai M, Gertsch J, Suter A, Heinrich M, Kortenkamp A.J Pharm Pharmacol. Mild interactions of echinacea include: astragalus; maitake ; Echinacea has mild interactions with at least 69 different drugs.

Initial dosage adjustments and cautious titration are recommended in patients with a creatinine clearance below 40 mL/min and/or liver disease.Moderate Potential Hazard, Moderate plausibility.



Because beta-1 selectivity is not absolute, the lowest possible dose of these agents should be used. Zebeta (bisoprolol) drug interactions.

Summary: Drug interactions are reported only by a few people who take Bisoprolol fumarate and Echinacea together. This site needs JavaScript to work properly. 2012 Feb 1;51(2):77-104. doi: 10.2165/11597910-000000000-00000.Drugs. Applies to: AllergiesThe use of beta-adrenergic receptor blocking agents (aka beta-blockers) in patients with a history of allergic reactions or anaphylaxis may be associated with heightened reactivity to culprit allergens. Use cautiously in patients with myasthenia gravis.Moderate Potential Hazard, Moderate plausibility. Applies to: hemodialysisTherapy with beta-adrenergic receptor blocking agents (aka beta-blockers) should be administered cautiously in patients requiring hemodialysis.

2009;69(13):1777-98. doi: 10.2165/11317010-000000000-00000. Unfortunately, many of the reviews on drug-herb interactions contain overstated or inaccurate information. Applies to: Cardiogenic Shock, HypotensionThe use of beta-adrenergic receptor blocking agents (aka beta-blockers) is contraindicated in patients with hypotension or cardiogenic shock. Applies to: TachyarrhythmiaBeta-adrenergic blockade in patients with Wolff-Parkinson-White syndrome and tachycardia has been associated with severe bradycardia requiring treatment with a pacemaker. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. There are 435 drug interactions with Zebeta (bisoprolol) Zebeta (bisoprolol) alcohol/food interactions.

Exacerbation of angina, myocardial infarction and ventricular arrhythmias have been reported in patients with coronary artery disease following abrupt withdrawal of therapy. Applies to: Ischemic Heart DiseaseHeightened sensitivity to catecholamines may occur after prolonged use of beta-adrenergic receptor blocking agents (aka beta-blockers).
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Applies to: Liver Disease, Renal DysfunctionBisoprolol is eliminated by both the kidney and liver. Available for Android and iOS devices.

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