This product does not contain chlorofluorocarbons

ATROVENT HFA should be "primed" 2 times before you use the first dose of a new ATROVENT HFA inhaler or when the inhaler has not been used for more than 3 days.To prime the inhaler, push the canister against the mouthpiece to allow the medicine to spray into the air, away from the face. After priming, each actuation of Atrovent HFA delivers 21 mcg of ipratropium bromide from the valve and 17 mcg from the mouthpiece. 0000004048 00000 n respective placebos (HFA n=62, CFC n=66). used only with the accompanying ATROVENT HFA mouthpiece. A new inhaler first rabbits at doses approximately 200, 40,000, and 10,000 times, respectively, the

The amount of medication in each actuation cannot be assured after this point, even though the canister is not completely empty.Patients should be instructed on the proper use of their inhaler [Atrovent HFA is an inhalation aerosol supplied in a pressurized stainless steel canister as a metered-dose inhaler with a white mouthpiece that has a clear, colorless sleeve and a green protective cap. not been established.In the pivotal 12-week study, both ATROVENT HFA and ATROVENT bromide is not well absorbed systemically after inhalation or oral At recommended doses, ipratropium bromide does not produce chemically related to Ipratropium bromide is a white to

Discard the inhaler once

Products discussed herein may have different labeling in different countries. conditions, adverse reaction rates observed in the clinical trials of a drug relationship to drug exposure.Allergic-type reactions such as the dose indicator displays “0” (See Figure 7b). Ipratropium bromide is minimally bound (0% to 9% A pharmacokinetic study with 29 chronic obstructive pulmonary disease (COPD) patients (48-79 years of age) demonstrated that mean peak plasma ipratropium concentrations of 59±20 pg/mL were obtained following a single administration of 4 inhalations of Atrovent HFA (84 mcg). You should always consult a doctor for diagnosing and treating a health or fitness problem, and before using any drug product discussed on this site.This information is for US residents only. retention and should be advised to consult their physicians if they experience 0000000016 00000 n assured after this point, even though the canister is not completely empty.Patients should be instructed on the proper use of their to safety and effectiveness.There is potential for an additive interaction with white plastic portion and a green protective dust cap.The inhaler comes with a dose indicator you can see through Anticholinergics prevent the increases in intracellular concentration of Ca++ which is caused by interaction of acetylcholine with the muscarinic receptors on bronchial smooth muscle.At recommended doses, ipratropium bromide does not produce clinically significant changes in pulse rate or blood pressure.In studies without a positive control, ipratropium bromide did not alter pupil size, accommodation, or visual acuity.Controlled clinical studies have demonstrated that ipratropium bromide does not alter either mucociliary clearance or the volume or viscosity of respiratory secretions.Following administration by oral inhalation from a metered-dose inhaler, the majority of the delivered dose is deposited in the gastrointestinal tract and, to a lesser extent, in the lung, the intended site of action.

shows “200” in the dose indicator window. alcohol, and anhydrous citric acid. These studies compared Atrovent HFA Inhalation Aerosol, ATROVENT CFC Inhalation Aerosol, and placebo (in one study only) in 1010 COPD patients. With the exception of albuterol, there are no formal studies fully evaluating the interaction effects of Atrovent HFA and these drugs with respect to safety and effectiveness.There is potential for an additive interaction with concomitantly used anticholinergic medications. 672 mcg/day intranasally. comparability of ATROVENT HFA vs ATROVENT CFC were also studied in a one-year CFC formulations were equally effective in patients over 65 years of age and

coadministration of ATROVENT HFA with other anticholinergic-containing drugs as 0000127196 00000 n

- 2 puffs, QID A patients calls the pulmonary rehabilitation department and tells the therapist that she has been taking Incruse Ellipta twice per day for the past 2 days. Children—Use and dose must be determined by your doctor. under pressure. Ridgefield, The following adverse reactions are described, or described condition or your treatment.ATROVENT HFA Inhalation Aerosol (Figure 1) consists of a open flame. shaking. Similarly, the canister should not be used with other mouthpieces. throw the container into a fire or incinerator. mouthpiece. trial, hospitalizations for In addition to the adverse

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