Amlodipine is one of the least likely DHPs to cause reflex tachycardia and therefore can be used in CHF as well as to control HTN and angina. This is an older generation of cholesterol lowering drugs, which bind up bile salts in the GI tract and cause their excretion, thus blocking the absorption of cholesterol. This is an unavoidable side effect mediated through the drugs mechanism of action.Bile acid sequesterant. Blocks activation of angiotensin II by binding to angiotensin I receptors. You should refer to the prescribing information for clindamycin for a complete list of interactions.Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use clindamycin only for the indication prescribed.Copyright 1996-2020 Drugs.com. Metoprolol succinate (Toprol XL) is given once daily and was shown through clinical trials to be the drug of choice for preventing cardio-remodeling.A class IB antiarrythmic. These side effects are first manifested as dizziness and slurred speech and can progress to seizures if toxic levels continue.

Some efficacy can be recovered if a loop/thiazide combination is employed. A major drug interaction can result when Gemfibrozil is used in combination with statins. This drug is contraindicated if a patient has a bad heart due to its extreme proarrythmic potential. CNS effects are a common side effect.HMG CoA reductase inhibitor (“statin”). Clindamycin works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. FDA indicated for angina, arrythmias and hypertension.Diuretic in the class of carbonic anhydrase inhibitors. The class as a whole moderately lowers LDL and may have some positive effects on HDL. However, in slow acetylators there is a possibility of development of a lupus-like syndrome.A class III antiarrythmic drug, indicated for chemical cardioversion (aka: acute termination of atrial fibrillation/flutter and adjustment to normal sinus rhythm). Indicated for ventricular tahycardia (V-tach), but not frequently used. Drug of choice in HF, as per clinical trials.Angiotensin Converting Enzyme Inhibitor (ACE-I) see Lisinopril (representative agent). See HydrochlorothiazideBile acid sequesterant (BAS), representative of its class. Like most of the other statins, it is metabolized via CYP 450 system in the liver. Blocks ACE leading to decrease in angiotensin II, decrease in aldosterone, inhibition of bradykinin breakdown and increases in vasodilatory prostaglandins. However, once the dosages are maxed renal patients will usually require dialysis. Associated with a unique lupus-like side effect. It is extremely proarrythmic due to its negative inotropic effects (which depress myocardial function). It is the only statin proven via clinical trials to decrease mortality via "primary prevention" (preventing the I of a patient's first MI), as well as "secondary prevention" (preventing MI reoccurrence). Due to its proarrthymic potential a patient's cardiogram must be closely followed to avoid torsades or branch bundle block. The class has fallen out of favor due to findings of the ALLHAT trial that demonstrated a 25% increase in cardiovascular events if used to treat HTN.

Tocainamide's side effect profile is similar to Lidocaine, however there is also a risk of blood dyscrasias, which requires a weekly CBC to be drawn for the first three months of therapy.A Potassium sparing diuretic, indicated in HTN. Indicated in patients post MI/stent placement. Established in 1876, the College of Pharmacy became the first pharmacy school in a public university.

See Atenolol.Cardioselective β-adrenergic antagonist. Indicated for SVT, V-tach and in emergency situations involving ischemia and hypoprofusion (eg; shock, HF). Unlike the statins the fibrates do not substantially lower LDLc, but are used to lower triglycerides (TG) and raise HDLc. Representative of its class.

It has no hematologic effects, but commonly causes GI distress. Indicated for myeloproliferative disorders. The risk of Medicines that interact with clindamycin may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with clindamycin.

It is indicated in infections caused by multiresistant bacteria.A Carbonic anhydrase inhibitor, used as a diuretic, most frequently used in glaucoma. Related to Digoxin, no longer used clinically.An “old world” drug, derived from the foxglove plant. See Amlodipine.A penicillin that shows ß-lactamase resistance and is acid stable, thus used in oral preparations.A non selective β-adrenergic antagonist. Tinnitus is common early in therapy. Recent evidence from clinical trials has demonstrated that Rosuvastatin may have the ability to dissolve plaque build up inside vessels resulting in "healing".

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