x��][���~7��Џ3�U�+X��ub;F,dI��%�����hd��Q��|�a����.NcaXӬ:$yz������������˻��럶oV�z�rw�?O_�v�}��������jw��?���x�z����݇�?�cp�w�f���� ~���y`�ڎ+;�u�?��O(/���ae�qm�� ;�_6�s��FiVJ�ڡ4�����V��U��5&�V�ȳ�����z��[G�2i���b�:&�4��� 4H���0k3I)�'ԙ�!�U���I8���!��`���Ip�<<3lDp Ҥ�e&��K2�VP�������&�`�F��;yH`��AJ2M^�e��:b��R�d2L����#�r2�$��g�R���(����L��T�%=87p䏓^��J2#x�Q��2,�-tp0S,I7Ap ��c�$;� Applies to: SeizuresLidocaine topical is absorbed through intact skin and mucosal membranes. Applies to: Heart Block, ShockLidocaine is absorbed through intact skin and mucosal membranes following topical administration. Ingestion of the drug has shown to result in seizures, severe brain injury, and heart problems in children.Major Potential Hazard, Moderate plausibility.

However, cross-sensitivity has been demonstrated occasionally with high dosages of these agents (e.g., acetaminophen >= 1000 mg), thus it may be appropriate to initiate therapy with low dosages and increase gradually.

There is some evidence suggesting that COX-2 inhibitors may be safely used in patients with aspirin-sensitive asthma, although the labeling for these products contraindicate such use.

Prolonged exposure, large doses, frequent applications and/or use on compromised skin or mucosa can produce systemic effects. D���S��(#(HS`��=����Cq(���$��F���'�yTR�Z�~MnDZΨYr� >�z| ��n�"�y5 H��X���'*!�̖M䬨������I�����pP&�UY@��,X��Pn����Y5������������6���ɖ#��|`)���� , ����Iy��+��H���X��*b� Serum concentrations of lidocaine and the active metabolites are increased and the half-life prolonged in patients with renal impairment. %PDF-1.5 Prolonged exposure, large doses, and/or application to compromised skin or mucosa can result in elevated plasma concentrations of lidocaine. Children and debilitated, elderly, or acutely ill patients should be given reduced dosages commensurate with their age, weight, and physical condition.Major Potential Hazard, Moderate plausibility. Enalapril (Vasotec®) Lisinopril (Prinivil®, Zestril®) Anticonvulsants: Carbamazepine (Carbatrol®, Epitol®, Tegretol®, Tegretol XR®) Divalproex sodium (Depakote®, Depakote ER®) Gabapentin (Gralise®, Horizant®, Neurontin®) Lacosamide (Vimpat®)- off-label Less than 10% is eliminated unchanged in the urine. If necessary, aspirin desensitization may also be attempted in some patients under medical surveillance.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. <> <>

<>>> �u��&��n=]�7#m�����0 <>/Font<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>> Applies to: Renal DysfunctionLidocaine topical is absorbed through intact skin and mucosal membranes. Enalapril Vasotec ® - Migraine prophylaxis ... Topical Agents Lidocaine cream, gel, jelly LC-4®, LC-5®, LMX 4®, LMX 5®, Recticare®, Topicaine®, Xylocaine® Local anesthesia, postherpetic neuralgia Burns, diabetic neuropathy Lidocaine patch Lidoderm® Salonpas® Postherpetic neuralgia Diabetic neuropathy Lidocaine/prilocaine cream, gel EMLA®, Oraqix®, Relador Pak®, … endobj Lidocaine is primarily eliminated by the kidney.

�x��[҉�Q�QPRXG�{KM*�ؽ�N��ɭB�Pht ���I�����蹤S$Z¦QG��x��$A���R)[��M����R�?�mϫ��5��Y�w�1\Q%^K:�`.j��`8�(�dC������`iԆ���JU�g����*�R�YQ��q 0������ň�Ä�0lQ1O�69Z%Q.�����3��lR +�0�dE+]�`E 3 0 obj

Therapy with lidocaine topical should be administered cautiously in patients with shock, sinus bradyarrhythmia, or severe heart block. Prolonged exposure, large doses, and/or application to compromised skin or mucosa can result in elevated plasma concentrations of lidocaine.

%���� The pharmacokinetic disposition of lidocaine is altered by changes in hepatic function, including hepatic blood flow.

Seizures can occur as a result of accumulation of active metabolites.

endobj

1 0 obj Lidocaine/Tetracaine lidocaine cream, lidocaine/prilocaine cream DIABETES Blood Glucose Meters & Test Strips Ascensia (Breeze, Contour) Roche (Accu-Chek) Trividia (TRUEtest, TRUEtrack) All other meters & test strips that are not listed as preferred Freestyle Kits/Meters: Freestyle Freedom, Freestyle Freedom Lite, Freestyle Insulinx, Freestyle Lite Prolonged exposure, large doses, and/or application to compromised skin or mucosa can result in elevated plasma concentrations of lidocaine. Lidocaine is primarily eliminated by the kidney. Applies to: Liver DiseaseLidocaine topical is absorbed through intact skin and mucosal membranes. Applies to: AsthmaApproximately 10% of patients with asthma may have aspirin-sensitive asthma, characterized by nasal polyposis, pansinusitis, eosinophilia, and precipitation of asthma and rhinitis attacks after ingestion of aspirin.

endobj Therapy with lidocaine topical should be administered cautiously and dosing modified for patients with compromised hepatic function.Major Potential Hazard, Moderate plausibility.

At high plasma levels, lidocaine can cause hypotension, bradycardia, and cardiovascular collapse. Salicylate salts, salsalate, salicylamide, and acetaminophen may be appropriate alternatives in patients with a history of NSAID-induced bronchospasm, since cross-sensitivity to these agents appears to be low.

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