IV. 2004 Aug;54(2):481-8. doi: 10.1093/jac/dkh338. Search ADS. Other studies have documented high rates of hospitalization among children with influenza, both for primary respiratory involvement and for complications such as reactive airway disease, encephalopathy, febrile convulsions, pericarditis, or involvement of other major organs [We gratefully acknowledge the participation of the patients, control subjects, families, primary care practitioners, and public health nurses throughout Iowa, without whom the study would not have been possible. Finally, because the definition of influenza-like illness is not agent-specific, we analyzed results of influenza-strain-specific convalescent-phase serologic testing from case patients and control subjects and found that patients were more likely than control subjects to have had a preceding infection with influenza A (H1N1).This study has several limitations. Please check for further notifications by email. Second, strains of influenza collected by sentinel physicians throughout the state from patients with influenza-like illness are characterized by the US World Health Organization Collaborating Laboratories in the region.A venous serum specimen for influenza-strain-specific convalescent serology was collected from patients and control subjects between 6 and 18 weeks after the patient's admission. 2007;44(suppl 2):S46, with additional informa- tion from references 9 through 11. Finally, pneumococcal pneumonia was confirmed in only 7 of the 13 children. A Diverse Physician-Scientist Pipeline to Fight Structural Racism Number and proportion of patients and control subjects with positive influenza A (H1N1) titer (≥1:40).Number and proportion of patients and control subjects with positive influenza A (H1N1) titer (≥1:40).Infection due to influenza is commonly considered vulnerable to complication by secondary bacterial pulmonary infections, notably by The theoretical bases for susceptibility to bacterial pneumonia following influenza infection are plentiful and include decreases in the function of polymorphonuclear leukocytes, macrophages, lymphocytes, and monocytes; increases in the adherence of bacteria to the respiratory epithelium; and decreased mucociliary clearance [Our study provides direct and indirect evidence that preceding infection with influenza A (H1N1) was a risk factor for severe pneumococcal pneumonia among previously healthy school children in Iowa.

Abstract. Crossref. Rockville, Maryland Likewise, family members of patients were more likely than those of control subjects to report experiencing an influenza-like illness in the 28 days preceding their admission date (OR, 2.6; 95% CI, 1.0–6.3). 2004 May;143(5):269-83. doi: 10.1016/j.lab.2004.02.002.Enferm Infecc Microbiol Clin. Current affiliation: Center for American Indian and Alaskan Native Health, Johns Hopkins School of Hygiene and Public Health, Baltimore.Katherine L. O'Brien, M. Ingre Walters, Jonathan Sellman, Patricia Quinlisk, Helen Regnery, Benjamin Schwartz, Scott F. Dowell, Severe Pneumococcal Pneumonia in Previously Healthy Children: The Role of Preceding Influenza Infection, An outbreak of severe pneumococcal pneumonia among children occurred in Iowa from November 1995 through January 1996.

However, in many countries strains of pneumococcus are becoming resistant to some of the commonly used antibiotics. By comparison, only 4 children had been admitted with a similar diagnosis in the preceding 24 months. The Lancet 2009;374:1543-56. 5 (pg. This unique and fortuitous situation allowed us to use single convalescent-phase serum samples to determine whether children had been infected with this strain of influenza during the current influenza season.Third, the case-control study revealed significant differences between the proportion of patients and their household members and of control subjects and their household members who had influenza-like illness before the admission of the patient. Search for other works by this author on: Your comment will be reviewed and published at the journal's discretion. PubMed. Search for other works by this author on: We identified 13 children with severe pneumococcal pneumonia. Name must be less than 100 characters The test is rapid and simple t… There are vaccines to help prevent pneumococcal disease. A urinary antigen test based on immunochromatographic membrane technique to detect the C-polysaccharide antigen of Available data show that pneumococcal bacteria are resistant to one or more antibiotics in 30% of cases.Following the introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) in 2000, antibiotic resistance initially declined before increasing again. Patients were more likely than control subjects to have a positive influenza A (H1N1) convalescent serology (matched OR, 3.7; 95% CI, 1.0–18.1).

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