You might also have jaw problems, but this is uncommon.Side effects are generally mild if you do get them. In addition, patients with other medical problems that can cause electrolyte imbalances or patients with kidney disease may need their dose of bisphosphate medication adjusted. Side effects for all the bisphosphonates (alendronate, ibandronate, risedronate and zoledronic acid) may include bone, joint or muscle pain. The three ways in which they can be taken (administered) are:Oral bisphosphonates tend to be poorly absorbed by the body and can cause irritation of the gullet (heartburn), so it's very important that you carefully follow the instructions for taking your medication:If you can't tolerate bisphosphonates by mouth it's possible to have them through a drip into a vein (intravenous infusion) or as an injection:Bisphosphonates are generally well tolerated. Bisphosphonates and denosumab don’t usually cause too many side effects. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. You might also have jaw problems, but this is uncommon. On this page about Maxolon you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information. Sign up and learn how to better take care of your body. Possible side effects include a fever and flu-like symptoms. Oversuppression of the osteoclasts can interfere with remodeling of the jaw so that tissue inside the bone dies. When taking an oral bisphosphonate, it is recommended that you remain upright for 30 to 60 minutes after taking the medication. Bisphosphonates are drugs that help prevent or slow down bone thinning (osteoporosis). While all medications have possible side-effects and risks, it is important to remember that there are also risks of not taking a necessary medication. Bisphosphonates are a group of drugs that work by slowing bone loss. They include indigestion and feeling sick (nausea) and flu-like symptoms after a bisphosphonate drip. Read our Rarely, bisphosphonates can cause damage to the jaw bone. If experienced, these tend to have a Less Severe expressionIf experienced, these tend to have a Less Severe expressionIf experienced, these tend to have a Severe expressionIf experienced, these tend to have a Less Severe expressionSelected from data included with permission and copyrighted by First Databank, Inc. Data suggests a higher chance of jaw osteonecrosis in patients taking bisphosphonate medications. He is an assistant professor at Harvard Medical School and an assistant attending physician in orthopaedic surgery at Massachusetts General Hospital. Side effects of the oral tablets may include nausea, difficulty swallowing, heartburn, irritation of the esophagus (tube connecting the throat to the stomach) and gastric ulcer. As you can see, the side effects of taking bisphosphonates are pretty bad— so bad, in fact, that a 2017 report in the medical journal BMJ found that approximately 1 in 5 people who started this drug cited adverse side effects as their reason for not continuing treatment.

Side effects that can occur in a minority of people shortly after receiving an IV bisphosphonate include flu-like symptoms, fever, headache and pain in muscles or joints. There's no clear evidence that this is harmful to the child. Possible side effects include a fever and flu-like symptoms. They reduce the risk of hip and spine fractures. General side effects of bisphosphonates and denosumab. Bone renewal is a slow process, but in many people an increase in bone density can be measured over five years of treatment.Bisphosphonates can be taken by mouth (orally), through a drip (intravenous infusion) or by injection.It's important to continue treatment as your doctor advises – even though you won't be able to feel whether it's working.Because longer-term treatment can sometimes have side-effects your doctor may suggest a break from treatment after 3–5 years.

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