2012 Feb;6(1):53-8. doi: 10.5489/cuaj.11037. Use of other alpha(1)-antagonists is also associated with IFIS. However there is no evidence of the usefulness of discontinuing the drug or using preoperative mydriatics. Urologists should inquire about the patient's glaucoma history from his/her ophthalmologist before starting an anticholinergic medication.Abstract Purpose: To evaluate structural alterations of iris and pupil diameters (PDs) in patients using systemic α-1-adrenergic receptor antagonists (α-1ARAs), which are associated with intraoperative floppy iris syndrome (IFIS). Medical management of symptomatic BPH is often preferred to surgical treatment as surgery increases the risk of morbidities, whereas, surgery is the main form of treatment to restore sight in patient with cataract. A telephone survey was used to determine previous use of tamsulosin, other alpha(1)-antagonists, and saw palmetto.

There was no significant difference between the saw palmetto and placebo groups in the change in AUASI scores (mean difference, 0.04 point; 95 percent confidence interval, -0.93 to 1.01), maximal urinary flow rate (mean difference, 0.43 ml per minute; 95 percent confidence interval, -0.52 to 1.38), prostate size, residual volume after voiding, quality of life, or serum prostate-specific antigen levels during the one-year study. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.WebMD does not provide medical advice, diagnosis or treatment.This survey is being conducted by the WebMD marketing sciences department.All information will be used in a manner consistent with the WebMD Stopping the alpha(1)-antagonist preoperatively is of questionable value.To describe the condition known as intraoperative floppy iris syndrome in association with systemic alpha-1 blocker use in patients undergoing cataract surgery and techniques to prevent related complications. All routine cases of cataract extraction with posterior chamber intraocular lens implantation between … Special mention is made on interactions with grapefruit juice, and mono amine oxidase (MAO) drug inhibitors. Please enable it to take advantage of the complete set of features! Intraoperative floppy iris syndrome (IFIS) was first described by Chang and Campbell [] as a triad of intraoperative signs during cataract surgery: flaccid iris stroma leading to billowing of the iris, iris prolapse through surgical wounds, and progressive intraoperative miosis.They also defined three grades of IFIS depending on the number of signs observed … The mean placebo effect on peak urinary flow rate was an increase of 1.20 (0.49) mL/s. In addition, reference lists from identified publications were reviewed to identify reports and studies of interest from 2001 to 2009. The biggest predicament being that an ophthalmologist is not likely to anticipate such challenges so an … Pertinent patient information, including age, gender, race, medical history, and current medication use (including tamsulosin [Flomax, Boehringer-Ingelheim, Ingelheim, Germany], other alpha(1)-antagonists, angiotensin antagonists, anticholinergics, cholinergic agonists, muscle relaxants, nitric oxide donors, and saw palmetto), were collected at the time of surgery. Acute angle closure glaucoma (AACG or closed angle glaucoma) is very rarely caused by anticholinergic medications in patients withnarrow angle anterior eye chambers.

In addition, reference lists from identified publications were reviewed to identify additional reports and studies of interest. The risk of intraoperative iris billowing was higher in rabbits included in tamsulosin group [OR=8.33 (CI 95% 0.63-110.09)], but insignificant statistically compare with control group (p= 0.13). RESULTS: There were no statistically significant differences between groups in rates of serious or non-serious adverse events, changes in vital signs, digital prostate exam findings, or study withdrawal rates. In this paper we have reviewed the syndrome, and offer practical information specially related to the origin and management of this syndrome and we offer practical information.Material and methodsA review of the related medical literature using PubMed and Cochrane databases.

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