Applies to: PheochromocytomaAdministration of beta-blockers alone in the setting of pheochromocytoma has been associated with a paradoxical increase in blood pressure due to the attenuation of beta-mediated vasodilatation in skeletal muscle. Applies to: HyperlipidemiaBeta-adrenergic receptor blocking agents (aka beta-blockers) may alter serum lipid profiles. Applies to: PsoriasisThe use of beta-blockers in psoriatic patients should be carefully weighed since the use of these agents may cause an aggravation in psoriasis.Moderate Potential Hazard, Moderate plausibility. Patients should be advised not to discontinue treatment without first consulting with the physician. In addition, the nonselective beta-blockers (e.g., propranolol, pindolol, timolol) may attenuate catecholamine-mediated vasodilation during exercise by blocking beta-2 receptors in peripheral vessels. It is important to tell your doctor about all other medications you use, including vitamins and herbs.

Applies to: Peripheral Arterial DiseaseDue to their negative inotropic and chronotropic effects on the heart, beta-adrenergic receptor blocking agents (aka beta-blockers) reduce cardiac output and may precipitate or aggravate symptoms of arterial insufficiency in patients with peripheral vascular disease. Applies to: Heart Block, Sinus Node DysfunctionThe use of beta-adrenergic receptor blocking agents (aka beta-blockers) is contraindicated in patients with sinus bradyarrhythmia or heart block greater than the first degree (unless a functioning pacemaker is present). Applies to: Ischemic Heart DiseaseHeightened sensitivity to catecholamines may occur after prolonged use of beta-adrenergic receptor blocking agents (aka beta-blockers). It acts by enhancing smooth muscle relaxation using nitric oxide, a chemical that is normally released in response to sexual stimulation. Propranolol is only part of a complete program of treatment that also includes diet, exercise, and weight control. The frequency and/or severity of attacks may be increased during beta-blocker therapy. Caution should be taken in the administration of these agents to patients suspected of having Prinzmetal's variant angina.Moderate Potential Hazard, Moderate plausibility. Applies to: Cardiogenic Shock, HypotensionThe use of beta-adrenergic receptor blocking agents (aka beta-blockers) is contraindicated in patients with hypotension or cardiogenic shock. In addition, these patients may be refractory to the usual doses of epinephrine used to treat acute hypersensitivity reactions and may require a beta-agonist such as isoproterenol.Major Potential Hazard, High plausibility. If signs or symptoms suggesting reduced cerebral blood flow are observed, consideration should be given to discontinuing these agents.Moderate Potential Hazard, Moderate plausibility. To minimize this risk, cessation of beta-blocker therapy, when necessary, should occur gradually with incrementally reduced dosages over a period of 1 to 2 weeks. Vidalista is the Medicine to Used to treat erectile dysfunction in men. the use of non-selective beta blockers is not recommended in these patients. Available for Android and iOS devices. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. Follow your diet, medication, and exercise routines very closely.Beta-adrenergic receptor blocking agents (aka beta-blockers) may alter serum lipid profiles. Close monitoring for progression of arterial obstruction is advised.Major Potential Hazard, High plausibility. Applies to: Myoneural DisorderBeta-adrenergic receptor blocking agents (aka beta-blockers) may potentiate muscle weakness consistent with certain myasthenic symptoms such as diplopia, ptosis, and generalized weakness. In patients who experience an exacerbation of angina following discontinuation of beta-blocker therapy, the medication should generally be reinstituted, at least temporarily, along with other clinically appropriate measures.Major Potential Hazard, High plausibility. Comprehensive alcohol & food interactions for InnoPran XL (propranolol). Available for Android and iOS devices. In general, the dosage required to achieve therapeutic blood concentrations in such patients may be higher than that required in euthyroid patients and should be individualized.Moderate Potential Hazard, Low plausibility. In addition, the 80 mg strength is a gray/white capsule imprinted with “80” and 2 segmented bands, while the 120 mg strength is a gray/off-white capsule imprinted with “120” and 3 segmented bands. Applies to: Glaucoma/Intraocular HypertensionSystemic beta-adrenergic receptor blocking agents (aka beta-blockers) may lower intraocular pressure.

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