Taking clomipramine together with medicines used during surgery or emergency treatment may increase the risk of side effects. All material on this website is protected by copyright, Copyright © 1994-2020 by WebMD LLC.

Glucovance is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.


Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.



GLUCOVANCE® (Glyburide and Metformin HCl) Tablets contain 2 oral antihyperglycemic drugs used in the management of type 2 diabetes, glyburide and metformin hydrochloride.. Glyburide is an oral antihyperglycemic drug of the sulfonylurea class.

Diseases & Conditions It works by restoring the balance of certain natural substances (serotonin, among others) in the brain. This medication may be available under multiple brand names and/or in several different forms. • Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma. These could be symptoms of a serious condition called drug reaction with eosinophilia and systemic symptoms (DRESS). The following conditions are contraindicated with this drug. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. informational and educational purposes only.

Clomipramine oral capsule is a prescription medication used to treat the excessive and repetitive ideas, thoughts, and impulses of obsessive-compulsive disorder. Do not use clomipramine with buspirone (Buspar®), fentanyl (Abstral®, Duragesic®), lithium (Eskalith®, Lithobid®), tryptophan, St. John's wort, or some pain or migraine medicines (eg, sumatriptan, tramadol, Frova®, Maxalt®, Relpax®, Zomig®). Check with your doctor if you are having an abnormal ejaculation or decreased sexual performance or desire. Check with your doctor first before taking any other medicines with clomipramine. If clomipramine is stopped, your doctor will tell you when to start taking clomipramine again after your surgery or procedure. Call your doctor for medical

Use clomipramine as ordered by your doctor. 805459-overview Drug Interactions (7)]. Using this website means you’re OK with this.

All rights reserved. Weight changes may occur during treatment with this medicine. You may report side effects to the FDA at 1-800-332-1088.

Available for Android and iOS devices. • Concomitant administration of bosentan [see . Let the doctor know if you, your child, or anyone in your family has bipolar disorder (manic-depressive) or has tried to commit suicide. Your list will be saved and can be edited at any time.The above information is provided for general

All drugs may cause side effects.

This is not a list of all drugs or health problems that interact with clomipramine. Do not start using clomipramine during the 2 weeks after you stop an MAO inhibitor. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.


This includes any possible side effects not listed in the package insert. DESCRIPTION. Be ready to tell or show what was

15 The change extended the label for all metformin-containing products to include patients with stable moderate renal failure (chronic kidney disease stage 3). Clomipramine is metabolised primarily by CYP2C19 isoenzyme via demethylation to form its active desmethylclomipramine metabolite, and by CYP2D6 isoenzyme via hydroxylation into its less active hydroxyclomipramine metabolites.

It may also cause some children, teenagers, and young adults to have suicidal thoughts and tendencies or to become more depressed. It may take several days to a few weeks to see a significant benefit. Be careful when using sharp objects, including razors and fingernail clippers. 2002

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