Reviewers will not be blinded to the authors or journals during this process.Variables for which data will be sought in the full text or abstract, if no full-text is available, of each selected study of interest include the following: (1) title, (2) first author, (3) design, (4) country, (5) publication year, (6) funding body (industry or drug company), (7) route of contrast (arterial or venous), (8) type of contrast (low/iso-osmolar or the actual name), (9) inclusion criteria, (10) exclusion criteria, (11) primary endpoint, (12) secondary endpoint, (13) drug(s) of interest, and (14) group (intervention and control).In addition, variables for which demographic data will be sought in each group consist of the following: (1) sample size, (2) sex (%: male/female), (3) mean age (years), (4) diabetes, (5) definition of chronic kidney disease (CKD) or renal insufficiency, (6) definition of contrast-induced nephropathy (CIN) or contrast-induced acute kidney injury (AKI), (7) definition of acute kidney injury (AKI) or acute renal failure (ARF), (8) mean contrast volume (ml), and (9) smoking status (%).Furthermore, variables for which kidney function will be sought in each group include the following: (1) mean baseline serum creatinine level (mg/dl) and standard deviation, (2) mean baseline glomerular filtration rate (GFR) (ml/min/1.73 mLastly, co-interventions and adverse events will serve as other variables for data extraction.The primary outcome of interest will be the risk of CI-AKI occurring after withholding the drugs. Radiology 183:111–114Choyke PL, Knopp MV (2003) Pseudohypocalcemia with MR imaging contrast agents: a cautionary tale. An in vitro study. You can also search for this author in CI-AKI is a sudden deterioration in renal function following the recent intravascular administration of a contrast medium in the absence of another nephrotoxic event.
These keywords were added by machine and not by the authors. Does Sotalol Interact with other Medications? Two reviewers (BL and OM) will independently screen the titles and abstracts of each potential relevant article to determine whether they meet the inclusion criteria. Radiology 183:111–114Crawford JA, Gumerman LW (1978) Alteration of body distribution of Tc99m-pyrophosphate by radiographic contrast material. This will allow patients at risk of developing CI-AKI or other adverse clinical outcomes to receive the proper care and treatment. In addition, this synthesis will enable clinicians to have a better understanding about which drugs should be stopped, when they should be stopped, and when they should be restarted after exposure to contrast material.
This process is experimental and the keywords may be updated as the learning algorithm improves. 2012;7(9):1103–10.Moher D, Liberati A, Tetzlaff J, Altman DG.

Outcome definitions in non-dialysis intervention and prevention trials in acute kidney injury (AKI). Am J Health Syst Pharm 59:1449–1553Choyke PL, Miller DL, Lotze MT et al (1992) Delayed reactions to contrast media after interleukin-2 immunotherapy. Randomized controlled trials will be evaluated using the Cochrane Risk of Bias (RoB) 2.0 tool for individually randomized, parallel group trials [Study data will be quantitatively synthesized by first assessing heterogeneity to examine whether the estimates from included studies could be pooled. Drug images are also included. Check mild interactions to serious contraindications for up to 30 drugs, herbals, and supplements at a time.

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