Levofloxacin is contraindicated in breast-feeding women. Cases of hypoglycaemic coma have been reported. driving a car or operating machinery). These are not all of the side effects that may occur. The risk of tendinitis and tendon rupture is increased in older patients, patients with renal impairment, patients with solid organ transplants, in patients receiving daily doses of 1000 mg levofloxacin and those treated concurrently with corticosteroids. You may also report side effects at https://www.fda.gov/medwatch. Levofloxacin solution for infusion is only intended for slow intravenous infusion; it is administered once or twice daily. heart failure, myocardial infarction, bradycardia)- elderly patients and women may be more sensitive to QTc-prolonging medications.

No adjustment of dose is required in the elderly, other than that imposed by consideration of renal function (see section 4.4 'tendinitis and tendon rupture' and 'QT interval prolongation').Levofloxacin is contraindicated in children and growing adolescents (see section 4.3).Levofloxacin solution for infusion is only intended for slow intravenous infusion; it is administered once or twice daily. For incompatibilities see 6.2 and compatibility with other infusion solutions see 6.6.Levofloxacin 5 mg/ml Solution for Infusion must not be used: Call your doctor or get medical Corticosteroids should not be used if signs of tendinopathy occur (see sections 4.3 and 4.8).Diarrhoea, particularly if severe, persistent and/or bloody, during or after treatment with levofloxacin, (including several weeks after treatment) may be symptomatic of Quinolones may lower the seizure threshold and may trigger seizures. If superinfection occurs during therapy, appropriate measures should be taken.Epidemiologic studies report an increased risk of aortic aneurysm and dissection after intake of fluoroquinolones, particularly in the older population.Therefore, fluoroquinolones should only be used after careful benefit/risk assessment and after consideration of other therapeutic options in patients with positive family history of aneurysm disease, or in patients diagnosed with pre-existing aortic aneurysm and/or aortic dissection, or in presence of other risk factors or conditions predisposing for aortic aneurysm and dissection (e.g. Tationil 600. Levofloxacin is contraindicated in patients with a history of epilepsy (see section 4.3) and, as with other quinolones, should be used with extreme caution in patients predisposed to seizures, or concomitant treatment with active substances which lower the cerebral seizure threshold, such as theophylline (see section 4.5). taken, how much, and when it happened. The infusion time must be at least 30 minutes for 250 mg or 60 minutes for 500 mg levofloxacin (see section 4.4). help if any of these side effects or any other side effects bother you or do not go away: https://www.webmd.com/drugs/2/drug-14497/levofloxacin-intravenous/details It is recommended that patients should not expose themselves unnecessarily to strong sunlight or to artificial ultraviolet (UV) rays (e.g. Avoid exposure to excess sunlight or artificial UV light. Very rare cases of prolonged (continuing months or years), disabling and potentially irreversible serious adverse drug reactions affecting different, sometimes multiple, body systems (musculoskeletal, nervous, psychiatric and senses) have been reported in patients receiving quinolones and fluoroquinolones irrespective of their age and pre-existing risk factors. • Dextrose 50 mg/ml (5%) in lactated Ringer's solution

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