Of those, 520 were taking statins; the others were not.While the study found a link between statin use and a reduced risk of depression, it did not prove that the drugs help patients avoid The message is not to take statins for depression risk, Whooley said, but that a possible benefit of the drugs, when they are needed, is to reduce depression risk. 2012 May;125(5):440-6. doi: 10.1016/j.amjmed.2011.11.013. The statins make the vessels less rigid, perhaps helping them adapt to the body's changing needs, she said.

Get information on depression symptoms, signs, tests, and treatments for many types of depression chronic depression and postpartum depression.Read more: Learn to Spot Depression: Symptoms, Warning Signs, Medication MedicineNet does not provide medical advice, diagnosis or treatment. Atypon Unable to load your delegates due to an error An 1999 Duke University study of healthy young women found that those with low cholesterol were more likely to have symptoms of depression and anxiety. It could also be that those who take statins are healthier overall than those who do not.

eCollection 2017.Hiles SA, Révész D, Lamers F, Giltay E, Penninx BW.Depress Anxiety. Epub 2012 Mar 2.Am J Cardiovasc Drugs.

2013;14(11):1467-1476. eCollection 2019.Adzic M, Brkic Z, Mitic M, Francija E, Jovicic MJ, Radulovic J, Maric NP.Curr Neuropharmacol. Expert Opin Pharmacother.

Since lovastatin was first approved in 1987 in the US, statins have become the leading pharmacologic treatment for high LDL-C … Statins are a class of drug that inhibit one of the first steps in cholesterol synthesis, in turn upregulating LDL receptors and lowering LDL-C generally by 25-50%. Cholesterol … A low serum cholesterol level has also been found to serve as a biological marker of major depression and suicidal behavior, whereas high cholesterol is protective 54–57. doi: 10.1016/j.ejcnurse.2010.08.008.

2017 Mar 31;12(3):e0174574.

Statins were hailed as miracle drugs when they were introduced in 1987.

A study found that heart disease guidelines may be missing the mark, particularly where African-Americans are concerned. Am J Cardiovasc Drugs. WEDNESDAY, Feb. 29 (HealthDay News) -- Patients who have heart disease and take cholesterol-lowering medicines known as statins are less likely to develop depression than those not on such drugs, a new study suggests.. For the study, Dr. Mary Whooley of the San Francisco VA Medical Center and colleagues evaluated 965 heart disease patients for depression. The child represents an extreme example of cholesterol inhibition, but his case illuminates the possible consequences of taking statins in strong doses or for a lengthy period of time–depression of mental acuity, anemia, acidosis, frequent fevers and cataracts. doi: 10.1371/journal.pone.0174574. Epub 2010 Jun 14.Kim SW, Kang HJ, Jhon M, Kim JW, Lee JY, Walker AJ, Agustini B, Kim JM, Berk M.Front Psychiatry.

You H, Lu W, Zhao S, et al. Remember that statin medications can reduce your risk of a heart attack or stroke, and the risk of life-threatening side effects from statins is very low. By Kathleen Doheny HealthDay Reporter. In the United States, about 36 million patients are eligible for statin prescriptions for On Tuesday, the U.S. Food and Drug Administration issued an update on statins, warning consumers that some statin users report The effects of the drugs on psychological well-being have been a topic of controversy, Whooley's team said.Exactly how the drugs may confer protection against depression isn't known. 2017 Jul 1;74(7):729-739. doi: 10.1001/jamapsychiatry.2017.0984.Huang CI, Lin LC, Tien HC, Que J, Ting WC, Chen PC, Wu HM, Ho CH, Wang JJ, Wang RH, Yang CC.PLoS One. Cholesterol is one of three end products in the mevalonate chain.

METHOD: Eight papers reporting the effect of statins on one or more of six mood states: depression, anxiety, anger, hostility, fatigue, confusion and vigour in adults older than 18 years were identified from a search of Cinahl, Medline and Cochrane electronic databases. 2002;58(9):1333.

2010;10(1):11-28. doi: 10.2165/13168600-000000000-00000.Vasc Endovascular Surg. This site needs JavaScript to work properly. Published in Neurology. 2010 Aug;44(6):421-33. doi: 10.1177/1538574410363833. SOURCES: Mary Whooley, M.D., physician, San Francisco VA Medical Center and professor of medicine, University of California, San Francisco; Bryan Bruno, M.D., acting chair of psychiatry, Lenox Hill Hospital, New York City; U.S. Food and Drug Administration Consumer Health Information; Feb. 21, 2012, Learn to Spot Depression: Symptoms, Warning Signs, Medication Atypon 2010;10 Suppl 1:10-7. doi: 10.2165/1158822-S0-000000000-00000.Minder CM, Blaha MJ, Horne A, Michos ED, Kaul S, Blumenthal RS.Am J Med. MYTH 3 Taking CoQ10 prevents muscle aches caused by statins. 3. According to the Centers for Disease Control and Prevention, 28 percent of Americans ages 40 and over were taking a cholesterol-lowering medication in 2012—and the …

Authored by Gaist, et al.) Heart disease was the leading cause of death in the U.S., and the American College of Cardiology says that statin therapy, which lowers cholesterol levels, reduces the risk of heart attack and stroke in patients who have or are at risk for atherosclerotic cardiovascular disease (ASCVD).

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