Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster . Eur J Clin Pharmacol 63 (2007): 875-885. Although you may experience remission a few years after starting treatment, the disease often returns if the drug is discontinued. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.
Lennard L, Van Loon JA, Weinshilboum RM "Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism." N Engl J Med 359 (2008): 1524-671. Am J Med 84 (1988): 960-477. de Fonclare AL, Khosrotehrani K, Aractingi S, Duriez P, Cosnes J, Beaugerie L "Erythema Nodosum-like Eruption as a Manifestation of Azathioprine Hypersensitivity in Patients With Inflammatory Bowel Disease." N Engl J Med 331 (1994): 883-450. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. Commonly reported side effects of azathioprine include: infection, nausea, leukopenia, and vomiting. Ann Rheum Dis 47 (1988): 503-59. However, permanent hepatic damage associated with Veno-occlusive disease of the hepatic veins is due to an unknown mechanism, may affect males more often, usually precedes Idiosyncratic manifestations of hypersensitivity include general malaise, headache, Azathioprine should be permanently withdrawn after occurrence of hypersensitivity reactions.Azathioprine-induced hypotension is independent of dose and may accompany signs and symptoms of hypersensitivity. Liver transplants most often use livers from deceased organ donors. All rights reserved. Lancet 347 (1996): 215-98. Escousse A, Mousson C, Santona L, Zanetta G, Mounier J, Tanter Y, Duperray F, Rifle G, Chevet D "Azathioprine-induced pancytopenia in homozygous thiopurine methyltransferase-deficient renal transplant recipients: a family study."

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Other side effects not listed may also occur in some patients.

Connell WR, Kamm MA, Dickson M, Balkwill AM, Ritchie JK, Lennardjones JE "Long-term neoplasia risk after azathioprine treatment in inflammatory bowel disease." Advances in biotherapy include new data on monoclonal antibodies (infliximab in … Skin lesions resolved 30 days after drug withdrawal.Excess sun exposure, pale skin types, and duration of allograft seem to be important risk factors in the development of skin lesions.Elevation in serum creatinine and BUN accompanied by oliguria are usually associated with hypotension, and normalize after treatment with intravenous hydration and steroids. J Hepatol 23 (1995): 351-489. Acute tubulointerstitial nephritis and no active glomerulonephritis were observed on renal biopsy. Agarwal SK, Mittal D, Tiwari SC, Dash SC, Saxena S, Saxena R, Mehta SN "Azathioprine-induced pure red blood cell aplasia in a renal transplant recipient."
Indications for methotrexate in ulcerative colitis alone were azathioprine intolerance (31 of 42) and lack of benefit from azathioprine (11 of 42). J R Soc Med 78 (1985): 1052-383. Can Med Assoc J 126 (1982): 512-319. By Gayle Holland Fat burning is accelerated with … Konstantopoulou M, Belgi A, Griffiths KD, Seale JR, Macfarlane AW "Azathioprine-induced pancytopenia in a patient with pompholyx and deficiency of erythrocyte thiopurine methyltransferase." If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. Hypersensitivity reactions: general malaise, dizziness, nausea, vomiting, diarrhoea, fever, rigors, exanthema, rash, myalgia, arthralgia, renal dysfunction and hypotension. Available from: URL: http://www.tga.gov.au/adr/aadrb/aadr0612.htm."

Silman AJ, Petrie J, Hazleman B, Evans SJ "Lymphoproliferative cancer and other malignancy in patients with rheumatoid arthritis treated with azathioprine: a 20 year follow up study." Liver 7 (1987): 81-348. O 074. Assini JF, Hamilton R, Strosberg JM "Adverse reactions to azathioprine mimicking gastroenteritis." Mycophenolic acid may cause your body to overproduce white blood cells. Ann Rheum Dis 48 (1989): 342-668. Clin Pharmacol Ther 46 (1989): 149-545. ([2006 Dec]):41. Lancet 342 (1993): 1245-622. Leukopenia (any degree) has been reported in greater than 50% of renal homograft recipients and 28% of rheumatoid arthritis patients. Chest 83 (1983): 696-894. During a living-donor liver transplant, you receive only a portion of a healthy liver from a living donor. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. The colitis remained in remission in seven of eight of those with RA treated with methotrexate and ulcerative colitis … Ann Rheum Dis 49 (1990): 25-762. Infusion reactions can occur, and the health team will watch for signs of a reaction during your infusion. METHODS: Patients with ulcerative colitis treated with oral methotrexate at the inflammatory bowel disease clinics of Oxford and Wycombe General Hospital, UK, were evaluated. Am J Gastroenterol 98(9S) (2003): S2422. Death associated with pancytopenia has been reported in patients with absent TPMT activity receiving azathioprine. Arch Dermatol 132 (1996): 1254-580. Public Health England advises avoid (refer to Green Book). Cerner Multum, Inc. "UK Summary of Product Characteristics."

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