(See BOX WARNING, CONTRAINDICATIONS, and PRECAUTIONS: Drug Interactions. )SPORANOX® Capsules should not be administered for the treatment of onychomycosis in patients with evidence of ventricular dysfunction such as congestive heart failure (CHF) or a history of CHF. ®Toenails with or without fingernail involvement: The recommended dose is 200 mg (2 capsules) once daily for 12 consecutive weeks.Fingernails only: The recommended dosing regimen is 2 treatment pulses, each consisting of 200 mg (2 capsules) b.i.d. It may be represented by the following structural formula and nomenclature:SPORANOX® Capsules contain 100 mg of itraconazole coated on sugar spheres. capsules should not be administered for the treatment of in patients with evidence of ventricular dysfunction such as congestive heart failure (CHF) or a history of CHF. Skipping doses can increase your risk of infection that is resistant to medication. Doses above 200 mg/day should be given in two divided doses.In life-threatening situations, a loading dose should be used.Although clinical studies did not provide for a loading dose, it is recommended, based on pharmacokinetic data, that a loading dose of 200 mg (two capsules) three times daily (600 mg/day) be given for the first 3 days of treatment.Treatment should be continued for a minimum of 3 months and until clinical parameters and laboratory tests indicate that the active fungal infection has subsided. Medication Guides, Drug Safety Communications, Shortages, Recalls. Doses above 200 mg/day should be given in two divided doses.In life-threatening situations, a loading dose should be used.Although clinical studies did not provide for a loading dose, it is recommended, based on pharmacokinetic data, that a loading dose of 200 mg (2 capsules) three times daily (600 mg/day) be given for the first 3 days of treatment.Treatment should be continued for a minimum of three months and until clinical parameters and laboratory tests indicate that the active fungal infection has subsided. An inadequate period of treatment may lead to recurrence of active infection.SPORANOX® Capsules and SPORANOX® Oral Solution should not be used interchangeably. Caution should be exercised when this drug is administered in this patient population. Itraconazole is an antifungal drug effective against most fungal infections in cats and dogs. This includes prescription and over-the-counter medicines, Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Sporanox only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Copyright 1996-2020 Cerner Multum, Inc. The median dose was 200 mg/day. Get the latest information on food recalls and alerts, including allergy alerts : You can also get the Food Safety Widget to display food safety alerts and recalls on your Web site. 2, D&C Red No. (See CLINICAL PHARMACOLOGY: Special Populations and PRECAUTIONS for further information. An inadequate period of treatment may lead to recurrence of active infection.SPORANOX® Capsules and SPORANOX® Oral Solution should not be used interchangeably. The mean time to overall success was approximately 10 months. The Center for Drug Evaluation and Research (CDER) ensures that safe and effective drugs are available to improve the health of the people in the United States Caution should be exercised when this drug is administered in this patient population (see CLINICAL PHARMACOLOGY, Special Populations and PRECAUTIONS).Limited data are available on the use of oral itraconazole in patients with hepatic impairment. Treatment should continue for 2 weeks following resolution of symptoms. SPORANOX® may affect the way other medicines work, and other medicines may affect how SPORANOX® works. Clinical signs and symptoms of oropharyngeal candidiasis generally resolve within several days.For patients with oropharyngeal candidiasis unresponsive/refractory to treatment with fluconazole tablets, the recommended dose is 100 mg (10 mL) b.i.d. Follow all directions on your prescription label and read all medication guides or instruction sheets.Do not share this medicine with another person, even if they have the same symptoms you have.Measure liquid medicine carefully. 22 and D&C Red No. )SPORANOX® (itraconazole) Capsules should be taken with a full meal to ensure maximal absorption. 28.SPORANOX® (itraconazole) Capsules should be taken with a full meal to ensure maximal absorption.SPORANOX® Capsules is a different preparation than SPORANOX® Oral Solution and should not be used interchangeably.The recommended dose is 200 mg once daily (2 capsules). Doses above 200 mg/day should be given in two divided doses.In life-threatening situations, a loading dose should be used.Although clinical studies did not provide for a loading dose, it is recommended, based on pharmacokinetic data, that a loading dose of 200 mg (2 capsules) three times daily (600 mg/day) be given for the first 3 days of treatment.Treatment should be continued for a minimum of three months and until clinical parameters and laboratory tests indicate that the active fungal infection has subsided. )Itraconazole Capsules should be taken with a full meal to ensure maximal absorption. Itraconazole is a 1:1:1:1 racemic mixture of four diastereomers (two enantiomeric pairs), each possessing three chiral centers.

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