Data sources include IBM Watson Micromedex (updated 2 Sep 2020), Cerner Multum™ (updated 1 Sep 2020), … The body naturally responds to bleeding by narrowing the blood vessel to slow blood flow.
NIMOTOP® (nimodipine) capsules are formulated as soft gelatin capsules for oral administration. The contents should then be emptied into the patient’s In patients who develop adverse reactions the dose should be reduced as necessary or the treatment discontinued.Severely disturbed liver function, particularly liver cirrhosis, may result in an increased bioavailability of nimodipine due to a decreased first pass capacity and a reduced metabolic clearance.
Hepatic impairment: Decrease dose to 30 mg (10mL) PO q4hr; closely monitor BP and HR. DO NOT ADMINISTER NIMOTOP CAPSULES INTRAVENOUSLY OR BY OTHER PARENTERAL ROUTES (see We comply with the HONcode standard for trustworthy health information -
Nimotop is given orally in the form of ivory colored, soft gelatin 30 mg capsules for subarachnoid hemorrhage. https://www.webmd.com/drugs/2/drug-10951/nimodipine-oral/details
Grapefuit juice is to be avoided (See Nimodipine capsules may be used during anaesthesia or surgical procedures.
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The other ingredients are microcrystalline cellulose, hypromellose, macrogol, maize starch, povidone, crospovidone, magnesium stearate and the colourings titanium dioxide (E171) and iron oxide yellow (E172). Applies to the following strengths: 30 mg; 60 mg/20 mL; 30 mg/10 mL; 30 mg/5 mL; 60 mg/10 mL60 mg orally, nasogastric, or gastric tube every 4 hoursPatients with cirrhosis: 30 mg orally every 4 hoursConcomitant use with strong CYP450 3A4 inducers/inhibitors: Avoid use.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Nimotop®(nimodipine) belongs to the class of pharmacological agents known as calcium channel blockers. Prophylactic administration should commence within four days of onset of subarachnoid haemorrhage and should be continued for 21 days. What Nimotop tablets contain The active substance is nimodipine.
Side Effects.
In the event of surgical invention, administration of nimodipine should be continued, with dosages as above, to complete the 21 day period.If the capsule cannot be swallowed, e.g., at the time of surgery, or if the patient is unconscious, a hole should be made in both ends of the capsule with an 18 gauge needle, and the contents of the capsule extracted into a syringe.
The soft gelatin capsule shell contains gelatin, glycerin, purified water and titanium dioxide.
USES: Nimodipine is used to decrease problems due to a certain type of bleeding in the brain (subarachnoid hemorrhage-SAH).Nimodipine is called a calcium channel blocker.
Although not all of these side effects may occur, if they do occur they may need medical attention.
The recommended dose is two tablets at 4-hourly intervals (total daily dose 360 mg) to be taken with water. Nimotop is given orally in the form of ivory colored, soft gelatin 30 mg capsules for subarachnoid hemorrhage.Unless otherwise prescribed, the oral dose is 60 mg (two 30 mg capsules) every 4 hours for 21 consecutive days. Dosage should be reduced to one 30 mg capsule every 4 hours with close monitoring of blood pressure and heart rate; if necessary, discontinuation of the treatment should be considered.Upon co-administration with CYP 3A4 inhibitors or CYP 3A4 inducers a dose adjustment may be necessary.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Subarachnoid Hemorrhage (Orphan) New dosage form. Orphan designation for intraventricular injection for treatment of subarachnoid hemorrhage. peppermint oil, purified water and polyethylene glycol 400.
reduction in blood pressure, may be more pronounced in these patients. Nimodipine is a yellow crystalline substance, practically insoluble in water. Dosage Modifications. In general, the capsules should be swallowed whole with a little liquid, preferably not less than one hour before or two hours after meals. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Renal impairment: Supplemental dose not necessary in hemodialysis or peritoneal dialysis. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products.
Sponsor A parenteral syringe can be used to extract the liquid inside the capsule, but the liquid should always be transferred to a syringe that cannot accept a needle and that is designed for administration orally or via a naso-gastric tube or PEG.
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