British Heart Foundation. Research has also shown that people taking Mevacor (lovastatin) have higher levels of atrogin-1 than those not taking the drug. The risk is small but important enough that the Food and Drug Administration (FDA) has issued a warning on statin labels regarding blood glucose levels and diabetes.The increase generally occurs when blood sugar levels are already higher than normal and fall in the prediabetes or diabetes range when you begin taking a statin.Statins prevent heart attacks in people with diabetes, so the relevance of the mild increase in sugar values with statins observed in some people is unclear. Yasmine S. Ali, MD, MSCI, is a board-certified preventive cardiologist and lipidologist. Read Newsmax Newsmax, Moneynews, Newsmax Health, and Independent. While statins are highly effective and safe for most people, they have been linked to muscle pain, digestive problems and mental fuzziness in some people who take them and may rarely cause liver damage.Statins include atorvastatin (Lipitor), fluvastatin (Lescol XL), lovastatin (Altoprev), pitavastatin (Livalo), pravastatin (Pravachol), rosuvastatin (Crestor, Ezallor) and simvastatin (Zocor, FloLipid).Having too much cholesterol in your blood increases your risk of heart attacks and strokes. Statin-related muscle problems are more likely to occur in people who exercise vigorously, especially if they begin to do so at a rapid rate rather than slowly building up intensity. A study from the University of California, San Diego School of Medicine, published August 22 online by PLoS ONE, reports that muscle problems reported by patients taking statins were related to the strength or potency of the given cholesterol-lowering drugs.. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins. This causes your liver to remove cholesterol from your blood.If you think you're experiencing side effects from statins, don't just stop taking the pills. As with any drug, you should bring up any concerns you have with your doctor to ensure that this is still the right treatment plan for you, and you should never stop taking a prescribed medication without your doctor's OK. These side effects reverse once you stop taking the medication. The proposed mechanism may also explain why heart muscle, which has different gatekeeper proteins for calcium release, is protected from any potentially harmful effects of statins.Dr Sarah Calaghan, Associate Professor in Cardiac Physiology from the University of Leeds said:"The idea that exercise makes statin side effects worse might be a misconception -- what really matters is the intensity of exercise. So, if your pain is localized to only one area of your body, then it’s probably related to something else. www.sciencedaily.com/releases/2019/08/190826191928.htm (accessed September 15, 2020).Below are relevant articles that may interest you. Millions of Americans take statins because they effectively target all aspects of one's British Heart Foundation. Muscle pain, the most common, is experienced by up to 9 percent of the patients who take them.

Have any problems using the site? However, studies have found that nearly 30 percent of people stopped taking the pills because of muscle aches even when they were taking a placebo.A strong predictor you'll experience muscle aches when taking statins could be whether or not you read about the potential side effect.Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Discuss these steps with your doctor before trying them:Although side effects believed to be caused by statins can be annoying, consider the benefits of taking a statin before you decide to stop taking your medication. Subscribe. While statins are proven to help reduce cholesterol, they come with a variety of risks and side effects. A common side effect of statin medications is muscle pain in major muscle groups. It's thought that simvastatin (Zocor) may be more likely to cause muscle pain as a side effect than other statins when it's taken at high doses. Fluvastatin and pravastatin, two relatively low potency statins that are not metabolized by CYP3A4, carry the lowest risk of rhabdomyolisis; high dose simvastatin (80 mg) carries the highest risk.

Sometimes switching to a different type of statin can resolve muscle-related pain and side effects, so your doctor may recommend this if you're in search of relief. In a Cochrane Foundation Analysis of 37,939 individuals involved in nine clinical trials, 9.4% of those receiving statins experienced myalgia, a rate similar to those of the participants who were given a placebo. You wouldn't need any additional liver enzyme tests unless you begin to have signs or symptoms of trouble with your liver.Contact your doctor immediately if you have unusual fatigue or weakness, loss of appetite, pain in your upper abdomen, dark-colored urine, or yellowing of your skin or eyes.It's possible your blood sugar (blood glucose) level may increase when you take a statin, which may lead to developing type 2 diabetes.

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