It has a molecular weight of 764.89.Zolpimist is available as an oral solution designed to be sprayed directly into the mouth over the tongue. You may report side effects to FDA at 1-800-FDA-1088.This Medication Guide summarizes the most important information about Zolpimist. Women appear to be more susceptible to this risk because they eliminate zolpidem from their bodies more slowly than men.Because use of lower doses of zolpidem will result in lower blood levels in the morning, FDA is requiring the manufacturers of Ambien, Ambien CR, Edluar, and Zolpimist to lower the recommended dose.FDA is continuing to evaluate the risk of impaired mental alertness with other insomnia drugs, including over-the-counter (OTC) drugs available without a prescription.FDA prepared a list of questions and answers to provide an additional overview of this safety issue. The lack of a drug interaction following single-dose administration does not predict a lack following chronic administration.An additive effect on psychomotor performance between alcohol and zolpidem was demonstrated A single-dose interaction study with zolpidem 10 mg and fluoxetine 20 mg at steady-state levels in male volunteers did not demonstrate any clinically significant pharmacokinetic or pharmacodynamic interactions. The total number of available doses is dependent on the number of actuations per dose (1 or 2 actuations) and the frequency of priming.Zolpidem tartrate, like other sedative-hypnotic drugs, has CNS-depressant effects. Zolpidem did not accumulate in young adults following nightly dosing with 20 mg zolpidem tartrate for 2 weeks.A food-effect crossover study in 14 healthy young (18-45 years of age) male subjects compared the pharmacokinetics of Zolpimist 10 mg when administered while fasting at least 8 hours or 5 minutes after eating a standard high-fat meal. The proper mixing sequence for TriCor 75 DF Herbicide and recommended tank-m ixtures is as follows: 1. *Reactions reported by at least 1% of patients treated with zolpidem tartrate and at a greater frequency than placebo.The frequencies presented, therefore, represent the proportions of the 3,660 individuals exposed to zolpidem tartrate, at all doses, who experienced an event of the type cited on at least one occasion while receiving zolpidem tartrate. Now go directly to Step 11.7.

The child-resistant container should be thrown away when the 60 sprays have been used.There are no special requirements for cleaning and maintaining Zolpimist.

The FDA Alert(s) below may be specifically about Zolpimist or relate to a group or class of drugs which include Zolpimist (zolpidem). A study involving haloperidol and zolpidem revealed no effect of haloperidol on the pharmacokinetics or pharmacodynamics of zolpidem. See the FDA Drug Safety Communication for a Data Summary.Healthcare professionals and patients are encouraged to report adverse events or side effects related to the use of these products to the FDA's MedWatch Safety Information and Adverse Event Reporting Program:Audience: Family Practice, Health Professional, PatientFDA is also reminding the public that all drugs taken for insomnia can impair driving and activities that require alertness the morning after use. ZOLPIMIST is a federally controlled substance (C-IV) because it can be abused and lead to dependence. Chemically, zolpidem is Zolpidem tartrate is a white to off-white crystalline powder that is sparingly soluble in water, alcohol, and propylene glycol. The value of dialysis in the treatment of overdosage has not been determined, although hemodialysis studies in patients with renal failure receiving therapeutic doses have demonstrated that zolpidem is not dialyzable.As with the management of all overdosage, the possibility of multiple drug ingestion should be considered.

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