Thank you for asking at HCM. I have allergy in my noise snd i cant taste anything but when i tiik diprofos 2ml injection i become better now after 2 month the allergy return..my question is it ok to take another injection?? Published studies provide evidence of efficacy and safety in pediatric patients for the treatment of nephrotic syndrome ( > 2 years of age), and aggressive lymphomas and leukemias ( > 1 month of age). Table 3 summarizes the drug classes which may either increase or decrease Phenytoin serum levels.Table 4 summarizes the drug classes whose serum levels and/or effects may be altered by Phenytoin.Although not a true pharmacokinetic interaction, tricyclic antidepressants and phenothiazines may precipitate seizures in susceptible patients and phenytoin dosage may need to be adjusted.Phenytoin may cause a slight decrease in serum levels of total and free thyroxine, possibly as a result of enhanced peripheral metabolism. Neoplastic Diseases Although a cause and effect relationship has not been established, the occurrence of lymphadenopathy indicates the need to differentiate such a condition from other types of lymph node pathology. . The loading dose should be followed by maintenance doses of 100mg orally or intravenously every 6 to 8 hours.In neonates, it has been shown that absorption of phenytoin is unreliable after oral administration, but a loading dose of 15-20mg/kg of phenytoin intravenously will usually produce serum concentrations of 10–20 mg/l phenytoin which is within the generally accepted therapeutic range. The clinically effective range is usually 10- 20mg/1 although some cases of tonic-clonic seizures may be controlled with lower serum levels of phenytoin.Intramuscular administration should not be used in the treatment of status epilepticus because peak plasma levels may not be reached for up to 24 hours.The intravenous route of administration is preferred. An acute myopathy has been observed with the use of high doses of corticosteroids, most often occurring in patients with disorders of neuromuscular transmission (eg, myasthenia gravis), or in patients receiving concomitant therapy with neuromuscular blocking drugs (eg, pancuronium). Peaple told us we need to wait 6 months Thank. Were I treating you, I would not suggest you injectable corticosteroid for allergic rhinitis because of long term side effects and complications, especially because many safe and alternative options are available for allergic rhinitis … The diluted form is suitable for use as long as it remains free of haziness and precipitate.Phenytoin should neither be mixed with other drugs nor be added to dextrose or dextrose-containing solutions due to the potential for precipitation of phenytoin acid.Continuous monitoring of the electrocardiogram and blood pressure is essential and the patient should be observed for signs of respiratory depression. Nystagmus on lateral gaze usually appears at 20mg/l and ataxia at 30mg/l. Arrhythmias including bradycardia, atrial and ventricular depression and ventricular fibrillation can occur and these have, in some cases, resulted in asystole/ cardiac arrest and death.

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Intra-Articular and Soft Tissue Administration And if yes for how long van i keep taking and does it threat my life for long term ?? Non-synaptic effects to reduce sodium conductance, enhance active sodium extrusion, block repetitive firing and reduce post-tetanic potentiation.2. Negative nitrogen balance due to protein catabolism. Neurologic/Psychiatric Intra-articular injection may result in damage to joint tissues. • Propylene glycol: Propylene glycol in this medicine can have the same effects as drinking alcohol and increase the likelihood of side effects. It allows continued monitoring of the benefit/risk balance of the medicinal product. Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment in asthma, atopic dermatitis, contact dermatitis, drug hypersensitivity reactions, perennial or seasonal allergic rhinitis, serum sickness, transfusion reactions. Concurrent use of corticosteroids with potassium-depleting diuretics may enhance Clinical improvement or recovery after stopping corticosteroids may require weeks to years. For time periods less than one week, the patient switched from intramuscular administration should receive half the original oral dose for the same period of time the patient received phenytoin intramuscularly. Day 1: 4-8 mg IM. However, as the pharmacologically active free drug concentration is unlikely to be altered, under these circumstances therapeutic control may be achieved with total phenytoin levels below the normal range 10 - 20mg/l. Psychic derangements may appear when corticosteroids are used, ranging from euphoria, insomnia, mood swings, personality changes, and severe depression to frank psychotic manifestations.

If such signs and symptoms occur, the patient should be evaluated immediately. In this case, alternative therapy should be an antiepileptic drug not belonging to the hydantoin chemical class.Acute alcoholic intake may increase phenytoin serum levels while chronic alcoholic use may decrease serum levels.Phenytoin may precipitate or aggravate absence seizures and myoclonic seizures. .

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