may email you for journal alerts and information, but is committed Members of _ can log in with their society credentials below The calcium channels are primarily arteriolar dilators . the site you are agreeing to our use of cookies. You can be signed in via any or all of the methods shown below at the same time.The email address and/or password entered does not match our records, please check and try again. This facilitates flooding of venules and leaks into the peri venular interstitial space.

Despite a compelling indication for angiotensin-converting en- zyme inhibitor (ACE-I) therapy (heart failure), this was precluded by a history of ACE-I-induced angioedema. However, after a month, she remained persistently hypertensive and was restarted on amlodipine 5 mg. It may be apt…
We presented a case of angioedema likely triggered by amlodipine.A 67-year-old African American woman with chronic hypertension continued to demonstrate subop- timal blood pressure control despite ongoing therapy with hydralazine and metoprolol. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Objective: Use of amlodipine for treatment of arterial hypertension and stable coronary artery disease (CAD) is sometimes limited by occurrence of peripheral edema and headache.We aimed to explore the true magnitude of this phenomenon by determining the … Message: Symptoms began to subside within 1 hour of receiving steroids and antihistamines, gradu- ally improved over the next 2 days, and required no additional therapy. Folder Name: 301-223-2300 For information on cookies and how you can disable them visit our You may be trying to access this site from a secured browser on the server. Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License ( In addition to arteriolar vasodilatation and increased vascular permeability, a role for bradykinin and vascular ni- trous oxide production has been postulatedThe investigation of angioedema should take into consideration unlikely drug-induced causes, and CCBs should be added to that list.This study was approved by our institutional review board.This article does not contain any studies with human or animal subjects.There are no human subjects in this article and in- formed consent is not applicable.

800-638-3030 (within USA), 301-223-2300 (international)Registered users can save articles, searches, and manage email alerts.Your message has been successfully sent to your colleague.Some error has occurred while processing your request. Your Name: (optional) Background A pre-specified subgroup analysis in an earlier, large-scale, placebo-controlled study suggested that amlodipine might reduce the risk for death in patients with heart failure due to a nonischemic cardiomyopathy. Your Name: (optional) If we look at clinical trial studies of amlodipine that looked at thousands of patients, the number of people experiencing swelling appears to be related to the dose taken.

Simply select your manager software from the list below and click on download. We present a case of angioedema likely triggered by amlodipine.Hypersensitivity reactions to dihydropyridine cal- cium channel blockers (CCB) are exceedingly rare, although sporadic reports of isolated angioedema seem to be gradually increasing in frequency.


The e-mail addresses that you supply to use this service will not be used for any other purpose without your consent.Create a link to share a read only version of this article with your colleagues and friends. By continuing to browse Approximately 2 weeks into amlodipine therapy, the patient awoke on three consecutive mornings with periorbital and lip angioedema (The amlodipine was discontinued, and the swelling resolved over the next day. Please try after some time.Get new journal Tables of Contents sent right to your email inbox

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