In many cases, Gingival hyperplasia can be a recurrent condition despite improvements in oral hygiene, professional treatment, and drug substitutions.

Introduction. It often begins in childhood, but it may not be noticeable until adulthood.

© 2005-2020 Healthline Media a Red Ventures Company. All rights reserved. doi: 10.2165/00002018-199615030-00007. 2014 Jan;5(1):59-66. doi: 10.4103/0976-237X.128666. In other cases, treatment depends on the underlying cause. This site needs JavaScript to work properly. Gingival enlargement produces aesthetic changes, pain, gingival bleeding and periodontal disorders. 1998 Dec;73(12):1196-9. doi: 10.4065/73.12.1196.J Clin Periodontol. It can also be drug-induced, as a side effect of prescribed medications. If your teeth are covered, they will be difficult to clean. This could increase your risk of developing gum disease. Gingival hyperplasia can be a recurrent condition despite improvements in oral hygiene, professional treatment, and drug substitutions. These 3 classes of drugs produce important changes in fibroblast function, which induce an increase in the extracellular matrix of the gingival connective tissue. Its true incidence in the general population is unknown. The gingival overgrowth from this condition is caused by an overproduction of collagen. Springer Gingival enlargement, an abnormal growth of the periodontal tissue, is mainly associated with dental plaque-related inflammation and drug therapy. eCollection 2017.Miranda-Rius J, Brunet-Llobet L, Lahor-Soler E, Ramírez-Rámiz A.BMJ Case Rep. 2014 Sep 8;2014:bcr2014206761. Other causes can be categorized into groups: inflammatory gum enlargement, systemic causes, and hereditary gingival fibromatosis.Gingival hyperplasia can occur as a direct result of inflammation. In more severe cases, your gums can completely cover your teeth, making it difficult to maintain effective oral hygiene habits. Mayo Clin Proc. 2019 Jan-Dec;33:2058738419828259. doi: 10.1177/2058738419828259.Open Dent J. Phenytoin and its metabolites have a direct action on the high-activity fibroblast population present in the gingiva leading to a subsequent increase in collagen production.

Hereditary gingival fibromatosis (HGF) is a rare oral condition that causes slow, progressive gum enlargement.

If you’re experiencing irregular symptoms or if you’re © 2005-2020 Healthline Media a Red Ventures Company. Gingival hyperplasia is an overgrowth of gum tissue around the teeth. Name must be less than 100 characters

Though many medications and combinations of medications are available for the phenytoin (PHT), gingival fibroblasts proliferate, causing tissue overgrowth and gingival hyperplasia.2 The drugs which have been reported to produce gingival hyperplasia can be categorized as follows: anti- epileptics, calcium channel blockers and immune-suppressants. 2017 Jul 31;11:420-435. doi: 10.2174/1874210601711010420. If you develop gingival overgrowth at a younger age, it could affect tooth eruption or the process where your teeth grow in and become visible.Gingival (gum) overgrowth is often caused by inflammation. Clipboard, Search History, and several other advanced features are temporarily unavailable. If left untreated, this oral condition can affect the alignment of your teeth and increase the risk of developing Other symptoms associated with gum overgrowth include:In more severe cases, the gums can completely cover the teeth, affecting hygiene and teeth alignment.

The inflammation can make the gums tender and red, and it can trigger bleeding. doi: 10.2165/00002018-199615030-00007. The term “gingival hyperplasia” usually used to describe an oral phenomenon seems nowadays used inappropriately because enlargement is not the result of an increase in the number of cells, but rather an increase in extracellular tissue volume. Gingival hyperplasia, similar to that seen with phenytoin and ciclosporin, is a rare but well-recognized adverse effect of nifedipine [88]. The gingival fibroblasts can also metabolise phenytoin and this may determine the susceptibility of the patient to phenytoin-induced gingival enlargement.

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