JWiren  RGMitchell  EThalen  ABToogood These results suggest that corticosteroids compete with warfarin for binding to HSA to site I .

 DJensin

 PESmail  CHRosier Ip  MDRooks  AAllam

 R Pharmacokinetics and metabolism of budesonide, a selective glucocorticoid.  HHochhaus

 CENelson  JOlsson

Prahl  BJ Comparative adrenal suppression with inhaled budesonide and fluticasone propionate in adult asthmatic patients.

 PH Long-term effect of inhaled corticosteroids on growth rate in adolescents with asthma.  APCrompton  P Steroid aerosols and cataract formation.

 EP Absence of posterior subcapsula cataracts in young patients treated with inhaled glucocorticoids.  M Effect of a volumatic spacer and mouth rinsing on systemic absorption of inhaled corticosteroids from a metered dose inhaler and dry-powder inhaler.  LPedersen

ScienceDirect ® is a registered trademark of Elsevier B.V.Insight into the interaction of inhaled corticosteroids with human serum albumin: A spectroscopic-based studyx00027;an Jiaotong University.

Conflict of interest: M. Weatherall has nothing to disclose.

 PTsanakas  EEvan Houwelingen  SR Use of inhaled corticosteroids and the risks of cataracts.

 SSorva

 HOhlsson  PRyrfeldt  AY Pupura and dermal thinning associated with high dose inhaled corticosteroids.  HWendt

McCubbin

 EEvan Houwelingen Although an overnight in-laboratory evaluation with sampling for plasma cortisol every hour or every 2 hours was required, it was clearly the most reliable test to evaluate suppression in our study population.

 PLTeelucksingh

 JWReed

Steroid naive asthma subjects (n = 156) were enrolled at six centers. Nebulised budesonide in a 1 mg (1,000 μg) dose produced anti-asthmatic and systemic effects equivalent to 35 mg and 7.6 mg of prednisone, respectively 9.  PTsanakas  SRLopez  JM Dynamic nature of posterior subcapsular cataract.

Adrenal suppression Tinkelman  A An assessment of the systemic effects of single repeated doses of inhaled fluticasone propionate, in inhaled budesonide in healthy volunteers. Hodsman

This was only possible for end points of adrenal suppression, where there were sufficient evaluable data, namely, for effects on 8 AM plasma or serum cortisol levels and on urinary cortisol (or cortisol-creatinine) excretion (24-hour or overnight). For the reasons discussed previously, it is pertinent to evaluate absolute cortisol values in studies of asthmatic patients but not in healthy volunteers.

 AAPHFrost

doi: 10.1002/14651858.CD002308.pub2.Cochrane Database Syst Rev.  NCMarone

Clark  ANussinovitch Dahl

 MHWarner  HOhlsson  S Knemometry, urine cortisol excretion, and measures of the insulin-like growth factor access and collagen turnover in children treated with inhaled glucocorticosteroids.  S  DBMullen  et al.  RLundback  GJackson

Falcoz  et al.  EB Inhaled steroid use and glaucoma [letter].

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