Updated DESCRIPTION Pitocin (oxytocin injection, USP) is a sterile, clear, colorless aqueous solution of synthetic oxytocin, for intravenous infusion or intramuscular injection.

Oxytocin Injection, USP (synthetic) is indicated for the medical rather than the elective induction of labor. Closer to 1960, scientists (or rather, V. D. Wine) has learned to make a synthetic copy. Elective induction of labor is defined as the initiation of labor for convenience in an individual with a term pregnancy who is free of medical indications. Intramuscular injection shows a dose of 0.5–1 IU in the period of 45-60 min. Consideration should, therefore, be given to the possibility of water intoxication, particularly when oxytocin is administered continuously by infusion and the patient is receiving fluids by mouth.Severe hypertension has been reported when oxytocin was given three to four hours following prophylactic administration of a vasoconstrictor in conjunction with caudal block anesthesia. Even with proper administration and adequate supervision, hypertonic contractions can occur in patients whose uteri are hypersensitive to oxytocin.Except in unusual circumstances, oxytocin should not be administered in the following conditions: prematurity, borderline cephalopelvic disproportion, previous major surgery on the cervix or uterus including caesarean section, overdistention of the uterus, grand multiparity or invasive cervical carcinoma. Treatment of Incomplete or Inevitable Abortion. If uterine contractions become too powerful, the infusion can be abruptly stopped, and oxytocic stimulation of the uterine musculature will soon wane.An intravenous infusion of a non-oxytocin containing solution should be started. Oxytocin injection is a sterile aqueous solution containing synthetic oxytocin.

Synthetic oxytocin does not possess the cardiovascular effects, such as elevation of blood pressure, as exhibited by vasopressin found in posterior pituitary injection. 55154-9584-5 Until the beginning of XX century this process took place in conjunction with various kinds of complications, often leading to death.And only in the early 1900’s, one of the specialists has been committed to the opening of the reproductive system of animals has been shown the hormone can stimulate uterine contractions, which contributed to termination of pregnancy.This hormone is called «Oxytocin», to the middle of the century it was used exclusively in its natural form. And this happens towards the end of pregnancy.Most often the drug occurs by intramuscular injection, as its composition is very sensitive to stomach acid.

Copy the URL below and paste it into your RSS Reader application. Abortion was successfully induced in 62 of 68 patients in the 9th to the 26th week of pregnancy be serial intramuscular administration of 15(S)-15-methyl-prostaglandin F2alpha (15-ME-PGF2alpha). Clipboard, Search History, and several other advanced features are temporarily unavailable. 20 IU in 1 litre of Ringer lactate or 0.9% sodium chloride, administered over 2 hours (160 drops/minute). In such cases, the effectiveness of the drug is minimized.Oxytocin in pregnancy used for stimulation of uterine walls, allowing you to cause spasmodic contraction, necessary for a speedy delivery. Each mL of Oxytocin Injection, USP synthetic (intended for intravenous infusion or intramuscular injection) possesses an oxytocic activity of 10 USP oxytocin units and contains Chlorobutanol Anhydrous (Chloral Derivative) 0.5%. This product may … Intravenous Infusion ( Drip Method )—To control postpartum bleeding, 10 to 40 units of oxytocin may be added to 1,000 mL of a nonhydrating diluent and run at a rate necessary to control uterine atony. The total dose of 1-3 IU.

Oxytocin stimulates rhythmic contractions of the uterus, increases the frequency of existing contractions and raises the tone of the uterine musculature.

If you are a consumer or patient please visit Acetic acid may have been added for pH adjustment (pH 3.0-5.0). August 10, 2020 General dose range: 2.5 mg to 100 mg IM. Contraception. The following dosage information is based upon the various regimens and indications in general use.Intravenous infusion (drip method) is the only acceptable method of administration for the induction or stimulation of labor.Accurate control of the rate of infusion flow is essential. initiated when the original abortion techniques, even when augmented by intravenous oxytocin, failed to produce expulsion of the fetus. Dosage and frequency of administration are also installed specialist. This product may contain up to 12.5% decomposition products/impurities. In the first trimester, curettage is generally considered primary therapy.

60 drops/minute) until efficient contractions are obtained (3 to 4 contractions lasting 40 seconds over 10 minutes). Hyperstimulation with strong (hypertonic) or prolonged (tetanic) contractions, or a resting tone of 15 to 20 mm H Dosage of oxytocin is determined by uterine response. As well as tool can be used nasal.

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