omeprazole vs famotidine for dogs ranitidine

This drug can also be used along with other treatments or as a supporting drug after surgery.However, it is important to point out that famotidine is Because there is no approved treatment guide for this medication, it is especially important to follow your vet’s directions.Most of the time, famotidine is used to treat gastrointestinal ulcers in dogs.Ulcers are produced when the stomach or intestines are damaged by the stomach acid or infections.

Experiment 2: 52 privately owned, conditioned Alaskan Husky sled dogs (16 female, 36 male, age range 2–8 years, with an average weight of 23.5 kg ± 3.0 kg SD) in 3 teams of 16 dogs each were randomly divided into 2 groups of 8 dogs each per team (omeprazole and high‐dose famotidine).

This is because it is often easier for the average pet owner to give a pet a tablet as opposed to an injection.Still, if a pet is not eating well, an injection might be given instead.Famotidine injections are also not FDA approved for use in dogs.Just like every medication, famotidine does have side effects that can affect your pooch.Luckily, the side effects are rare and often minimal. If a dose is missed, it is possible for stomach acid production to speed up and symptoms to reemerge.Famotidine usually comes in 10 milligrams (mg) tablets, though 20 mg tablets are sold as well. At the conclusion of the exercise challenge, dogs were fed and rested for 12 hours, then fasted for 12 hours.

Department of Small Animal Clinical Sciences, Texas A&M University, TAMU‐4474, College Station, TXDepartment of Statistics, Oklahoma State University, Stillwater, OKDepartment of Small Animal Clinical Sciences, Texas A&M University, TAMU‐4474, College Station, TXDepartment of Statistics, Oklahoma State University, Stillwater, OKThis work was completed at the Oklahoma State University Center for Veterinary Health Sciences, Glenallen, Alaska, and Big Lake, Alaska.Use the link below to share a full-text version of this article with your friends and colleagues. The race was completed in approximately 66 hours. Which name you’ll hear simply matters on your location and specific veterinarian.This medication works by reducing the production of stomach acid, which can help a number of conditions. These findings have important clinical implications not only for racing sled dogs, but potentially also for dogs faced with stress‐induced gastric ulceration/erosion from serious disease, trauma, surgery, or both.The 1st experiment was undertaken to determine if the efficacy of famotidine in a 100 mile experimental exercise challenge predicted its efficacy in a 330 mile race. Beginning 2 days before the exercise trial, drug administration was begun to dogs in both treatment arms. The dogs ran 330 and 300 miles in 66 and 52 hours in the 1st and 2nd studies, respectively. Dogs had not received antiulcer medications for at least 6 months before the start of the study. The latter decision was based upon ethical concerns.

Previous studies have consistently demonstrated a 41–61% incidence of gastric lesions in racing sled dogs,In the 2nd experiment, no comparison was made between high‐dose famotidine and an untreated or placebo control; therefore, no conclusion can be made as to the efficacy of high‐dose famotidine in preventing gastric ulcer formation. Endoscopy before exercise was possible because the exercise challenge was not a race, but an experiment performed under racing conditions. Dogs ran at an average speed of 10 mph.

This is why this medication is usually a favorite and prescribed by vets.The adverse effects of this medication have not been completely documented. Furthermore, although the decrease in prevalence of gastric lesions was statistically significant, the fact that nearly 50% of the treated dogs had clinically important gastric lesions demonstrated the need for a more efficacious treatment.The relatively poor efficacy of famotidine in the current experiments is surprising when one considers that the recommended dose of famotidine is 0.5 mg/kg q24h,The dose of omeprazole used in experiment 2 (and in the previously published studyIn summary, omeprazole administered at recommended doses was superior to famotidine administered at higher than recommended doses for decreasing the severity of gastric lesions in sled dogs running 300–330 miles. ‘Twice daily administration of a suspension of omeprazole [1mg/kg], was the only regimen tested that approached the potential therapeutic efficacy for acid-related disease when assessed by criteria used for human patients.’

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