In veterinary medicine, Co-amoxiclav (e.g. Japanese Journal of Antibiotics 39: 1733–1744, 1986Hitzenberger G, Korn A. Pharmacokinetics of co-trifamole in patients with disorders of kidney function. Journal of Chromatography 223: 139–145, 1981Gooch III WM. Journal of Antimicrobial Chemotherapy 16: 763–771, 1985Hofstetter A, Frisen A, Bishop-Freudling GB, Vergin H. Co-trimoxazol-Konzentration im prostateseknet von potienten mit subakuter und chronischer prostatitis.

You can see your Bookmarks on your Copy and paste the desired citation format or use the link below to download a file formatted for EndNoteTo get new article updates from a journal on your personalized homepage, please All DeepDyve websites use cookies to improve your online experience. Journal of Infectious Diseases 134: 476–485, 1976Parsons RL, Paddock GM. Pharmacokinetics of co-trimazine after single and multiple doses. J. vet. Antimicrobial Agents and Chemotherapy 28: 165–166, 1985Hughes DTD, Bye A, Hodder P. Levels of trimethoprim and sulphamethoxazole in blood and sputum in relation to treatment of chest infections.

Pharmacokinetics of the association of ticarcillin with clavulanic acid in renal insufficiency and during hemodialysis. Therapeutic doses of sulfonamides are usually administered PO except in acute life-threatening infections when IV infusions are used to establish adequate blood concentrations as rapidly as possible. Where one compound potentiates the effect of a second drug they may be coformulated. Amoxycillin trihydrate (Betamox LA 150mg/ml) 150mg/kg. D): 109–124, 1983aNorrby SR, Rogers JD, Ferber F, Jones KH, Zacchei AG, et al. Postgraduate Medicine (Augmentin Suppl. Amoxycillin/clavulanic acid: a review of its antibacterial activity, pharmacokinetics and therapeutic use. 6a): 165–167, 1985bNielsen ML, Hansen I. Trimethoprim in human prostatic tissue and prostatic fluid.

For therapy of arthritis, the CVMA-pug recommends potentiated sulfonamides. University of Glasgow, Glasgow, 1985aWatson ID. ): 59–67, 1975Patel RB, Welling PG. You can also search for this author in International Journal of Clinical Pharmacology, Therapy and Toxicology 23: 70–73, 1985Davies BE, Humphrey MJ, Langley PF, Lees L, Legg B, et al. Chemotherapy 20: 321–330, 1974Nordholm L, Dalgaard L. Determination of trimethoprim metabolites including conjugates in urine using high performance liquid chromatography with combined ultraviolet and electrochemical detection. A clinical study on imipenem/cilastatin sodium in the field of pediatrics. Over 10 million scientific documents at your fingertips Journal of Antimicrobial Chemotherapy 11: 435–445, 1983Royce C, Karran S, Williams S. Pharmacokinetics of Timentin (clavulanate potentiated ticarcillin) in patients undergoing biliary surgery. Carbapenems, a new class of antibiotics: discovery and development of imipenem/cilastatin. Acute toxic manifestations may be seen after too rapid IV administration or if an excessive dose is injected. American Journal of Medicine 79(Suppl. A high-performance liquid chromatography method for trimethoprim utilizing solid-phase column extraction. British Journal of Clinical Pharmacology 18: 183–193, 1984Vree TB, Heckster YA, Baars AM, Damsina JG, van der Kleijn E. Determination of trimethoprim and sulfamethoxazole (cotrimoxazole) in body fluids of man by means of high perform ance liquid chromatography. A small proportion of Salmonella and E. coli isolates were resistant to clavulanate‐potentiated amoxycillin.

Journal of Chromatography 107: 327–333, 1975Haginaka J, Nakagawa T, Nishino Y, Uno T. High performance liquid chromatographic determination of clavulanic acid in urine. Journal of Chromatography 145: 496–501, 1978cWalstad RA, Helium KB, Thurmann-Nielsen E, Dale G. Pharmacokinetics and tissue penetration of Timentin: a simultaneous study of serum, urine, lymph, suction blister and subcutaneous thread fluid. Because dogs are deficient in acetylation, they may be at risk of increased formation of phase I metabolites associated with adverse effects.

Sulfonamides are frequently added to drinking water or feed either for therapeutic purposes or to improve feed efficiency. Clavulanic acid and CP-45, 899: a comparison of their in vitro activity in combination with penicillins. 1 0 obj<> endobj 2 0 obj<>/Font<>/ProcSet[/PDF/Text]/ExtGState<>>> endobj 3 0 obj<>stream Springer Verlag, Vienna, 1983Dudley MN. Antimicrobial Agents and Chemotherapy 24: 290–292, 1983bWise R, Donovan IA, Drumm J, Andrews JM, Stephenson P. The penetration of amoxycillin/clavulanic acid into peritoneal fluid. Antimicrobial Agents and Chemotherapy 30: 896–900, 1986Jusko WJ. Start studying pyoderma treatment. Even potentiated sulfonamides, which are bactericidal, are time dependent in their antibacterial efficacy.Although all of the sulfonamides have the same mechanism of action, differences are evident with respect to activity, pharmacokinetic fate, and even antimicrobial spectrum at usual concentrations. The use of trimethoprim-sulfamethoxazole in children: a review of adverse reactions and indications.

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