You may report side effects to the FDA at 1-800-FDA-1088.This leaflet summarizes the most important information about tolterodine tartrate. If you suspect that you or anyone else who may have overdosed of Tolterodine Tartrate Tablet, please go to the emergency department of the closest hospital or nursing home. Incidence* (%) of Adverse Events Exceeding Placebo Rate and Reported in >1% of Patients Treated withablets (2 mg bid) in 12-week, Phase 3 Clinical Studiesbefore you start using it and each time you get a refill. There are no studies of tolterodine in pregnant women. Keep a list of them with you to show your doctor or pharmacist each time you get a new medicine.Medicines like tolterodine tartrate can cause blurred vision, dizziness, and drowsiness. A decision should be made whether to discontinue nursing or to discontinue tolterodine tartrate in nursing mothers.Efficacy in the pediatric population has not been demonstrated.Two pediatric phase 3 randomized, placebo-controlled, double-blind, 12-week studies were conducted using tolterodine extended release capsules. Medication discarded in this manner may contaminate the environment. In dogs, changes in the QT interval (slight prolongation of 10% to 20%) were observed at a suprapharmacologic dose of 4.5 mg/kg, which is about 68 times higher than the recommended human dose. Expired drug may become ineffective in treating your prescribed conditions. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Select one or more newsletters to continue. Please check for these effects on your body when using Tolterodine Tartrate Tablet. A total of 853 patients received tolterodine tartrate 2 mg twice daily and 685 patients received placebo. Some of the side-effects may be rare but serious. Study subjects [approximately equal representation of CYP2D6 extensive metabolizers (EMs) and poor metabolizers (PMs)] completed sequential 4-day periods of dosing with moxifloxacin 400 mg QD, tolterodine 2 mg BID, tolterodine 4 mg BID, and placebo. ), allergies, pre-existing diseases, and current health conditions (e.g. Always consult with your doctor for recommendations specific to your body and health conditions.Most medicines don’t come with a potential for addiction or abuse. The empirical formula of tolterodine tartrate is CTolterodine tartrate is a white, crystalline powder. In the event of difficulty in breathing, upper airway obstruction, or fall in blood pressure, tolterodine tartrate tablets should be discontinued and appropriate therapy promptly provided.Tolterodine tartrate tablets should be administered with caution to patients with clinically significant bladder outflow obstruction because of the risk of urinary retention and to patients with gastrointestinal obstructive disorders, such as pyloric stenosis, because of the risk of gastric retention (see Tolterodine tartrate, like other antimuscarinic drugs, should be used with caution in patients with decreased gastrointestinal motility.Tolterodine tartrate should be used with caution in patients being treated for narrow-angle glaucoma.Tolterodine tartrate is associated with anticholinergic central nervous system (CNS) effects including dizziness and somnolence (see Adverse Reactions). If you notice other effects not listed above, contact your doctor or pharmacist.Call your doctor for medical advice about side effects. Advise patients not to drive or operate heavy machinery until the drug's effects have been determined. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. Keep all Do not flush medications down the toilet or pour them into a drain unless instructed to do so. The 4 mg BID dose of tolterodine IR (two times the highest recommended dose) was chosen because this dose results in tolterodine exposure similar to that observed upon coadministration of tolterodine 2 mg BID with potent CYP3A4 inhibitors in patients who are CYP2D6 poor metabolizers (see Table 2 summarizes the mean change from baseline to steady state in corrected QT interval (QTc) relative to placebo at the time of peak tolterodine (1 hour) and moxifloxacin (2 hour) concentrations. By using this Site you agree to the following Read the Patient Information Leaflet if available from your pharmacist before you start using tolterodine and each time you get a refill. Tolterodine is a competitive muscarinic receptor antagonist. July 15, 2005. Properly discard this product when it is expired or no longer needed. Read the Patient Information Leaflet if available from your pharmacist before you start using tolterodine and each time you get a refill. Usually, government’s categorizes medicines that can be addictive as controlled substances. At these doses, the AUC values were about 20- to 25-fold higher than in humans. If experienced, these tend to have a Severe expression 1. Data sources include IBM Watson Micromedex (updated 2 Sep 2020), Cerner Multum™ (updated 1 Sep 2020), … Effects on urodynamic parameters before and 1 and 5 hours after a single 6.4 mg dose of tolterodine immediate release were determined in healthy volunteers. DETROL LA is available in 2 mg and 4 mg capsules. Every one of our associated gratification facilities have actually been authorized by the governing bodies from their corresponding nations.

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