Practice parameter: a guideline for discontinuing antiepileptic drugs in seizure-free patients—summary statement.
A detailed history is important to establish whether seizures were focal (partial) or generalized (involving bilateral hemispheres of the brain), and whether consciousness was impaired.
Grosso S, Nolan SJ, Evidence is insufficient to guide this decision for children with generalized seizures, and there is no evidence with which to answer this question for adults.
All rights Reserved. American Academy of Neurology Quality Standards Subcommittee. Neurology 1996; 47: 600 – 2. Early versus late antiepileptic drug withdrawal for people with epilepsy in remission. Randomised study of antiepileptic drug withdrawal in patients in remission. Stopping antiepileptic drugs: when and why? A guideline for discontinuing antiepileptic drugs in seizure-free patients-Summary Statement Report of the Quality Standards Subcommittee of the American Academy of Neurology The Quality Standards Subcommittee of the Ameri- can Academy of Neurology (AAN) develops practice parameters for neurologists pertaining to diagnostic
When people with epilepsy become seizure‐free with daily antiepileptic drug (AED) management, there is a very individual decision to be made about discontinuing this treatment. Hixson JD. After 1–6 years of seizure‐freedom, it is estimated that 69% of children and 61% of adults remain seizure‐free when AEDs are tapered and stopped. Giussani G, Five trials with a total of 924 children were ultimately included in the meta-analysis; the most recent trial was published in 2000.Four of the trials were conducted in affluent European countries, and one took place in Ethiopia. The American Academy of … Neonates were excluded.
The studies lasted from six months to seven years and included an initial taper of antiepileptic drugs over one month to one year. Practice parameter: a guideline for discontinuing antiepileptic drugs in seizure-free patients--summary statement. Report of the Quality Standards Subcommittee of the American Academy of Neurology. Report of the Quality Standards Subcommittee of the American Academy of Neurology American Academy of Neurology Quality Standards Subcommittee. Neurology. Wilden JA,
Report of the Quality Standards Subcommittee of the American Academy of Neurology. The following sections provide resources or links to epilepsy-related guidelines or practice parameters that may be useful for health care professionals.
See the CME Quiz Questions.Author disclosure: No relevant financial affiliations.In patients with a history of epilepsy, how long must one be seizure-free before stopping antiepileptic drug therapy?Children with epilepsy should be seizure-free for at least two years before stopping antiepileptic drug therapy, especially those who have partial seizures or a history of abnormal electroencephalography (EEG) results. Evidence-Based Guideline: Treatment of Convulsive Status Epilepticus in Children and Adults: Report of the Guideline Committee of the American Epilepsy SocietyNew Guideline for Treatment of Prolonged Seizures in Children and Adults A treatment algorithm that comprises three phases of treatment Keeping current on evidence-based guidelines and practice parameters is critical for epilepsy professionals to provide quality care to patients and families.
Cohen-Gadol AA. Furthermore, some patients may have had nonepileptic (psychogenic) seizures or seizures provoked by a resolved stimulus (e.g., fever, alcohol or drug withdrawal).The authors of this Cochrane review assessed the risk of discontinuing antiepileptic drug therapy in children and adults with true epilepsy.
Practice Parameter : A guideline for discontinuing antiepileptic drugs in seizure-free patients – Summary Statement Neurology 1996;47:600-602 Dr. Rafael Higashi (neurologist) Institute of Neurology Deolindo Couto UFRJ- Epilepsy Outpatient Unit
Wingerchuk DM, A guideline for discontinuing antiepileptic drugs in seizure-free patients – Summary Statement 1. Attempts should be made to retrieve EEG or imaging study results. Beghi E, 2005 Jan 15;71(2):384-386. Guidelines for Prescribing Antiepileptic Drugs.
Evaluation of first nonfebrile seizures. Copyright © 2016 by the American Academy of Family Physicians.Copyright © 2020 American Academy of Family Physicians. Withdrawal of antiepileptic drugs: guidelines of the Italian League Against Epilepsy. (Strength of Recommendation: B, based on inconsistent or limited-quality patient-oriented evidence. Practice Guideline Briefs CARRIE MORANTZ. Practice parameter: a guideline for discontinuing antiepileptic drugs in seizure-free patients--summary statement. Am Fam Physician. BRIAN TORREY. The Quality Standards Subcommittee of the American Academy of Neurology (AAN) develops practice parameters for neurologists pertaining to diagnostic procedures, treatment modalities, and clinical disorders.
Practice parameter: a guideline for discontinuing antiepileptic drugs in seizure … Sperling MR,
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