1827166-overview 20-50 mcg/kg/min IV (high dose): May increase blood pressure and stimulate vasoconstriction; may not have a beneficial effect in blood pressure; may increase risk of tachyarrhythmias
When taken with 51 meals high in bran fiber, however, the amount absorbed from an oral dose may be reduced. Treatment of hypotension, low cardiac output, poor perfusion of vital organs; used to increase mean arterial pressure in septic shock patients who remain hypotensive after adequate volume expansion1-5 mcg/kg/min IV (low dose): May increase urine output and renal blood flow 5-15 mcg/kg/min IV (medium dose): May increase renal blood flow, cardiac output, heart rate, and cardiac contractitlity20-50 mcg/kg/min IV (high dose): May increase blood pressure and stimulate vasoconstriction; may not have a beneficial effect in blood pressure; may increase risk of tachyarrhythmiasMay increase infusion by 1-4 mcg/kg/min at 10-30 min intervals until optimum response obtainedStrong beta1-adrenergic, alpha-adrenergic, and dopaminergic effects are based on dosing rate1-5 mcg/kg/min IV, increased to 5-20 mcg/kg/min; not to exceed 50 mcg/kg/min Orphan designation for prevention of intraventricular hemorrhage in premature neonatesCardiovascular: Ventricular arrhythmia, atrial fibrillation (at very high doses), ectopic beats, tachycardia, anginal pain, palpitation, cardiac conduction abnormalities, widened QRS complex, bradycardia, hypotension, hypertension, vasoconstrictionOcular: Increased intraocular pressure; dilated pupilsGangrene of extremities has occurred when high doses were administered for prolonged periods or in patients with occlusive vascular disease receiving low doses of dopamine hydrochlorideMay cause peripheral ischemia in patients with history of occlusive vascular diseaseIf ischemia occurs, prevent sloughing and necrosis in ischemic areas by infiltrating areas as soon as possible with 5-10 mg of phentolamine (adrenergic blocking agent) in 10-15 mL of saline solutionHypersensitivity to dopamine, pheochromocytoma, ventricular fibrillation, uncorrected tachyarrhythmiasUse caution in angina pectoris, extravasation, hypovolemia, occlusive vascular disease, ventricular arrhythmias, recent use of monoamine oxidase inhibitors, sensitivity to sulfitesUse caution in patients taking MAO inhibitors; prolong hypertension may occur with concurrent useLactation: Unknown whether drug is excreted into breast milk; use cautionA: Generally acceptable.
encoded search term (dobutamine ((dobutamine))) and dobutamine ((dobutamine)) Preoperative Noninvasive Cardiac Testing in Older Adults With Hip FractureNovartis to Provide 'No Profit' COVID-19 Drugs to Low Income CountriesEU Scrambles to Buy Intensive Care Drugs to Tackle COVID ShortagesVitamin D and Risk of All-cause and Cause-specific MortalityShare cases and questions with Physicians on Medscape consult. So, there are 24 doses (of 5 mL) in a 4 oz (120 mL) bottle. Chapter Five Dosage Calculations 5 Now set up your equation and solve for x. and formulary information changes. Acyclovir X Diluted to <5 mg/mL Infusion over 60 -90 minutes. 2010 Each maintenance dose is prepared by dissolving four 500 mg tablets in 150 mL of water. Diseases & Conditions The loading doses for each of the above indicated groups were 0.5, 0.5, 1 and 2.2 mcg/kg, respectively. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature.
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informational and educational purposes only. Maintenance Dose: Administer 10% to 20% of the loading dose required for response as a continuous infusion per hour and titrate. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. (3mg/ml) DOSE:0.05 -0.1 mg/kg up to 6 mg over 1 2 seconds followed by rapid NS flush. ), norepinephrine, potassium chloride(? Controlled studies in pregnant women show no evidence of fetal risk.Endogenous catecholamine, acting on both dopaminergic and adrenergic neuronsLow dose stimulates mainly dopaminergic receptors, producing renal and mesenteric vasodilation; higher dose stimulates both beta1-adrenergic and dopaminergic receptors, producing cardiac stimulation and renal vasodilation; large dose stimulates alpha-adrenergic receptorsMetabolized in liver, kidney, and plasma by monoamine oxidase and catechol-O-methyl transferaseMetabolites: Norepinephrine (active), inactive metabolitesAdditive: Acyclovir, alteplase, amphotericin B, ampicillin, gentamicin(?
2002 Starting 4 hours after the loading dose, give maintenance dose of 70 mg/kg/dose PO every 4 hours for 17 doses. This website also contains material copyrighted by 3rd parties. 151715-overview Procedures adenosine administrat 6 mg/2 mL. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvaW50cm9waW4tZG9wYW1pbmUtMzQyNDM1 ), verapamil (incompatible at higher concentrations)Y-site (partial list): Amiodarone, atracurium, calcium gluconate, ciprofloxacin, diazepam, diltiazem, dopamine, epinephrine, fentanyl, inamrinone, labetalol, lidocaine, lorazepam, magnesium sulfate, midazolam(?
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