Last updated on Jun 14, 2019. Other drugs that have the same active ingredients (e.g. tablet. Solifenacin may also be used for purposes not listed in this medication guide.You should not use this medicine if you have untreated or uncontrolled narrow-angle You should not use solifenacin if you are allergic to it, or if you have:trouble emptying your bladder (or you have a weak stream of urine);It is not known whether this medicine will harm an unborn baby. Vibramycin is a tetracycline antibiotic that fights bacteria in the body. Vibramycin is an antibacterial drug synthetically derived from oxytetracycline, and is available as Vibramycin Monohydrate (doxycycline monohydrate); Vibramycin Hyclate and Vibra-Tabs (doxycycline hydrochloride hemiethanolate hemihydrate); and Vibramycin Calcium (doxycycline calcium) for oral administration. Do not give VESIcare to other people, even if they have the same symptoms you have. The following adverse reactions have been identified during post-approval use of solifenacin succinate in the U.S. and/or outside of the U.S. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.Solifenacin is a substrate of CYP3A4.

The lowest GoodRx price for the most common version of generic Vesicare is around $14.49, 95% off the average retail price of $348.78. Generic name: SOLIFENACIN SUCCINATE 5mg. The placebo-subtracted mean changes (90% CI) in QTcF for moxifloxacin in the three sessions were 11 (7, 14), 12 (8, 17), and 16 (12, 21), respectively.The QT interval prolonging effect of the highest solifenacin succinate dose (three times the maximum therapeutic dose) studied was not as large as that of the positive control moxifloxacin at its recommended dose. It is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Available for Android and iOS devices. This case was associated with mental status changes. Anaphylactic reactions have also been reported in patients treated with solifenacin succinate. VESIcare Dosage. In some cases, angioedema occurred after the first dose, however, cases have been reported to occur hours after the first dose or after multiple doses.

VESIcare is contraindicated in patients with gastric retention VESIcare is associated with antimuscarinic central nervous system (CNS) adverse reactions VESIcare should be used with caution in patients being treated for narrow-angle glaucoma In a study of the effect of solifenacin succinate on the QT interval conducted in 76 healthy women The use of VESIcare is not recommended in patients at high risk of QT prolongation, including patients with a known history of QT prolongation and patients who are taking medications known to prolong the QT interval.Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.VESIcare has been evaluated for safety in 1811 adult patients in four randomized, placebo-controlled trials (Studies 1-4) In the four 12-week double-blind clinical trials, severe fecal impaction, colonic obstruction, and intestinal obstruction were reported in one patient each, all in the VESIcare 10 mg group. Indications and Usage for VESIcare.

For more information, ask your doctor or pharmacist.Medicines are sometimes prescribed for purposes other than those listed in Patient Information leaflets. Take your next dose at the regular time the next day and stay on your once-daily schedule.Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Avoid driving or hazardous activity until you know how this medicine will affect you. The majority of patients were Caucasian (93%) and female (80%) with a mean age of 58 years.The primary endpoint in all four trials was the mean change from baseline to 12 weeks in number of micturitions/24 hours. When these muscle contractions happen too often or cannot be controlled you can get symptoms of overactive bladder, which are urinary frequency, urinary urgency, and urinary incontinence (leakage).This Patient Information has been approved by the U.S. Food and Drug Administration. Medicines that may interact with VESIcare include pramlintide, anticholinergics, and some antibiotics. Angioedema and anaphylactic reactions may be life-threatening.

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