2007;58:85–91.Baldessarini RJ, Henk HJ, Sklar AR, Chang J, Leahy LF. Suicide in 406 mood-disorder patients with and without long-term medication: 40–44 year follow-up. You can also search for this author in 2018;20:708–20.Nielsen RE, Kessing LV, Nolen WA, Licht RW. We conducted a nonsystematic review of recent research reports and developed consensus among international experts on the use of lithium to treat major mood disorders, aiming for a simple but authoritative guide for patients and prescribers.We summarized recommendations concerning safe clinical use of lithium salts to treat major mood disorders, including indications, dosing, clinical monitoring, adverse effects and use in specific circumstances including during pregnancy and for the elderly.Lithium continues as the standard and most extensively evaluated treatment for bipolar disorder, especially for long-term prophylaxis.In 1949, John Cade (1929–1996), an Australian psychiatrist, serendipitously initiated a new era in psychiatric treatment by using lithium carbonate to treat mania. 2009;119:22–7.Vieta E, Günther O, Locklear J, Ekman M, Miltenburger C, Chatterton ML, et al. 2018;20:97–170.International Consortium for Research on Mood & Psychotic Disorders, McLean Hospital, Belmont, MA, USADepartment of Psychiatry, Harvard Medical School, Boston, MA, USALucio Bini Mood Disorders Centers, Lucio Bini Center, Via Cavalcanti 28, 09128, Cagliari and Rome, ItalyDepartment of Psychiatry, Dalhousie University, Halifax, NS, CanadaDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital Dresden, Dresden, GermanyDepartment of Psychiatry and Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, USADepartment of Psychiatry, Erasmus Medical Center, Rotterdam, The NetherlandsMood Disorders Center of Ottawa and Department of Psychiatry, University of Toronto, Toronto, CanadaDepartment of Clinical Medicine, Aalborg University, Aalborg, DenmarkAalborg University Hospital–Psychiatry, Aalborg, DenmarkDepartment of Pharmacology, Dalhousie University, Halifax, NS, CanadaSection of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, ItalyDrug Commission of the German Medical Association, Berlin, GermanyMedical Faculty, Bipolar Center, Sigmund Freud Private University, Wiener Neustadt, AustriaYou can also search for this author in 2017b;7:e015462–73.Kleindienst N, Greil W. Differential efficacy of lithium and carbamazepine in the prophylaxis of bipolar disorder: results of the MAP study. Med J Austr.
© 2020 BioMed Central Ltd unless otherwise stated. Delphi survey of maintenance lithium treatment in older adults with bipolar disorder: an ISBD task force report. 1998;50:261–7.Coppen A, Standish-Barry H, Bailey J, Houston G, Silcocks P, Hermon C. Does lithium reduce mortality of recurrent mood disorders? Int J Bipolar Disord. 1980;13:156–67.Lauterbach E, Felber W, Müller-Oerlinghausen B, Ahrens B, Bronisch T, Meyer T, et al. 2013;170:31–42.Thies-Flechtner K, Müller-Oerlinghausen B, Seibert W, Walther A, Greil W. Effect of prophylactic treatment on suicide risk in patients with major affective disorders: data from a randomized prospective trial. Br Med J. The syndrome of irreversible lithium-effectuated neurotoxicity.

2003;290:1467–73.Goodwin GM, Haddad PM, Ferrier IN, Aronson JK, Barnes T, Cipriani A, et al. WFSBP Task Force on Treatment Guidelines for Bipolar Disorders. 2012;22:339–46.Post RM, Leverich GS, Kupka RW, Keck PE Jr, McElroy SL, Altshuler LL, et al.

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