Neurological Long-term administration of amiodarone has been …

This site needs JavaScript to work properly. Thrombophlebitis of peripheral vein is a well recognised complication of intravenous amiodarone use in high doses (300–1200 mg) or prolonged infusion. Epub 2019 Sep 23.Am J Ther. Atrial fibrillation with rapid ventricular response, is the most common arrhythmia treated with amiodarone in a telemetry unit in one medical center located in northern California. We excluded studies of pediatric or nonhuman patients, secondary research reports (literature reviews and letters), and studies in which patients received amiodarone orally or via a central venous catheter.Increased surveillance is required with higher doses and concentrations of intravenous amiodarone.In the studies that met the inclusion criteria, we used review management softwareWe appraised study quality using the Evidence-based Librarianship Critical Appraisal checklist.To avoid reporting bias and overrepresentation of positive or significant results,Our search identified 216 records. This case demonstrates that even smaller doses of amiodarone can cause significant thrombophlebitis, if given in a small vein. We excluded 5 case studies, 1 systematic review, and 1 study that did not confirm phlebitis rate, retaining 11 studies in our systematic review. Version 5.2The Nordic Cochrane Centre, The Cochrane CollaborationCochrane Handbook for Systematic Reviews of InterventionsObtaining individual patient data from randomised controlled trialsSystematic Reviews in Health Care: Meta-analysis in ContextCochrane Handbook for Systematic Reviews of InterventionsAssessing the quality of randomised controlled trialsSystematic Reviews in Health Care: Meta-analysis in ContextProblems and limitations in conducting systematic reviewsSystematic Reviews in Health Care: Meta-analysis in ContextEmpirical assessment of effect of publication bias on meta-analysesSystematic reviews in health care: investigating and dealing with publication and other biases in meta-analysisThe PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaborationA critical appraisal tool for library and information researchEfficacy of i.v. The purpose of this research was to determine if peripheral IV amiodarone and vancomycin influenced the incidence of thrombophlebitis in an adult cardiothoracic population. The Intravenous Amiodarone Multicenter Investigators GroupIntravenous amiodarone in treatment of recent-onset atrial fibrillation: results of a randomized, controlled studyEfficacy and safety of short intravenous amiodarone in supraventricular tachyarrhythmiasConversion of recent onset paroxysmal atrial fibrillation to normal sinus rhythm: the effect of no treatment and high-dose amiodarone. Name must be less than 100 characters amiodarone in converting rapid atrial fibrillation and flutter to sinus rhythm in intensive care patientsAtrial fibrillation after cardiac surgery: does prophylactic therapy decrease adverse outcomes associated with atrial fibrillationThe incidence of phlebitis with intravenous amiodarone at guideline dose recommendationsAdvanced Cardiovascular Life Support Provider ManualAdministration of amiodarone during resuscitation of ventricular arrhythmiasIntravascular thrombophlebitis related to the peripheral infusion of amiodarone and vancomycinPrescribing amiodarone: an evidence-based review of clinical indicationsAcute thrombophlebitis following IV amiodarone administrationThrombophlebitis associated with peripheral amiodaroneVariation in intravenous amiodarone use - reducing adverse outcomes with an inpatient safety initiativePreventing complications of central venous catheterizationRisk of catheter-related bloodstream infection with peripherally inserted central venous catheters used in hospitalized patientsThe risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studiesThe problem with peripherally inserted central cathetersImproving Catheter Site Care. Phone, (800) 899-1712 or (949) 362-2050 (ext 532); fax, (949) 362-2049; email, Phlebitis severity grades (based on Infusion Nurses Society scaleOverall phlebitis rates among patients in included studiesPhlebitis rates and total doses of intravenous amiodaronePhlebitis rates and intravenous amiodarone infusion rates V: Hemolysis as a model for phlebitisBilateral upper extremity thrombophlebitis related to intravenous amiodarone: a case reportCordarone extravasation inducing Volkmann’s-like syndromeMethodology in conducting a systematic review of systematic reviews of healthcare interventionsSystematic review of the empirical evidence of study publication bias and outcome reporting bias - an updated reviewReview Manager (RevMan) [computer program]. SpieringDifferent study designs yielded variation in phlebitis rates. We found no overall relationship between infusion duration and phlebitis rate. Intravenous amiodarone is the gold-standard treatment for arrhythmias, but phlebitis is a common adverse effect.To determine the incidence and contributing factors of amiodarone-induced phlebitis and examine phlebitis severity.A systematic review was conducted of articles published before February 2016 in the Cumulative Index to Nursing and Allied Health Literature, Cochrane Library, MEDLINE, Embase, Web of Science, and gray databases (Bielefeld, Lenus, EUGrey, RIAN, and DART).

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