Medroxyprogesterone is also used to decrease the risk of endometrial hyperplasia (a condition that may lead to uterine cancer) while taking estrogens.Medroxyprogesterone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.You should not use medroxyprogesterone if you are pregnant, or if you have liver disease, a hormone-related cancer such as breast or uterine cancer, a history of stroke or blood clot, or abnormal vaginal bleeding that has not been checked by a doctor.Medroxyprogesterone should not be used to prevent heart disease, stroke, or dementia. Some medicines may make medroxyprogesterone acetate injectable suspension less effective at preventing pregnancy, including those listed below. Medroxyprogesterone acetate injectable suspension can pose an additional risk in patients with risk factors for osteoporosis (e.g., metabolic bone disease, chronic alcohol and/or tobacco use, anorexia nervosa, strong family history of osteoporosis or chronic use of drugs that can reduce bone mass such as anticonvulsants or corticosteroids).
The median study duration was 13 months with a range of 1 to 84 months.

You can ask your healthcare provider for information about medroxyprogesterone acetate injectable suspension that is written for healthcare providers.This Patient Information has been approved by the U.S. Food and Drug Administration. In a controlled, clinical study, adult women using medroxyprogesterone acetate injectable suspension for up to 5 years showed spine and hip BMD mean decreases of 5 to 6%, compared to no significant change in BMD in the control group. You may report side effects to Health Canada at 1-866-234-2345.Before using this medication, tell your doctor or pharmacist your medical history, especially of: family medical history (especially breast lumps and This drug may make you dizzy or drowsy. (Women who use medroxyprogesterone acetate injectable suspension may lose significant bone mineral density.

The Incident Rate Ratio (IRR) for any fracture during the follow-up period (mean = 5.5 years) was 1.41 (95% CI 1.35, 1.47). Medroxyprogesterone acetate (e.g., Depo-Provera Contraceptive, depo-subQ provera 104) is used parenterally for the prevention of conception.
BMD should be evaluated when a woman needs to continue to use medroxyprogesterone acetate injectable suspension long-term. Anaphylaxis and anaphylactoid reaction have been reported with the use of medroxyprogesterone acetate injectable suspension. (2000): age, ethnic group, socioeconomic status, and any combined estrogen/progestogen oral contraceptive use. Smoking greatly increases your risk of blood clots.This medicine can pass into body fluids (including urine, feces, vomit).

(g)   The effects of medroxyprogesterone acetate on lipid metabolism are inconsistent. Medroxyprogesterone is added to estrogen replacement therapy to reduce the risk of cancer of the uterus. If you would like more information, talk with your healthcare provider. Use of medroxyprogesterone acetate injectable suspension was associated with a significant decline from baseline in BMD.

There have been a few reported cases of convulsions in patients who were treated with medroxyprogesterone acetate injectable suspension. * Body System represented from COSTART medical dictionary. It is unknown if use of medroxyprogesterone acetate injectable suspension during adolescence or early adulthood, a critical period of bone accretion, will reduce peak bone mass and increase the risk for osteoporotic fracture in later life. Women who have or have had a history of breast cancer should not use hormonal contraceptives, including medroxyprogesterone acetate injectable suspension, because breast cancer may be hormonally sensitive Lee et al. In clinical studies, about 1 out of 100 women got pregnant during the first year that they used medroxyprogesterone acetate injectable suspension. It is a white to off-white, odorless crystalline powder, stable in air, melting between 200° and 210° C.

As women continue using medroxyprogesterone acetate injectable suspension, fewer experience irregular bleeding and more experience amenorrhea. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.Things to remember when you fill your prescription.WebMD does not provide medical advice, diagnosis or treatment.This survey is being conducted by the WebMD marketing sciences department.All information will be used in a manner consistent with the WebMD Know the medicines you take. It is a white or almost white, crystalline powder that is stable in air and that melts between 205°C and 209°C.

Discontinue medroxyprogesterone acetate injectable suspension use if jaundice or acute or chronic disturbances of liver function develop. Monitor patients who have a history of depression and do not re-administer medroxyprogesterone acetate injectable suspension if depression recurs. Your chance of getting pregnant depends on how well you follow the directions for taking your medroxyprogesterone acetate injectable suspension.

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