Individualize dosage by titration of the separate components. The mean age was 67 After single doses approximately 5, 1.5, and 1.0 times those achieved in humans with 100 mg losartan in combination with [see The usual starting dose of HYZAAR is 50/12.5 (losartan 50 mg/hydrochlorothiazide 12.5 mg) once daily. hypertension and left ventricular hypertrophy treated with atenolol had a lower risk of stroke, the primary of the National High Blood Pressure Education Program’s Joint National Committee on Prevention, HYZAAR 100/12.5, followed by HYZAAR 100/25. Initiate a patient whose blood pressure is not adequately controlled with losartan 100 mg monotherapy with HYZAAR 100/12.5 (losartan 100 mg/hydrochlorothiazide 12.5 mg) once daily. to losartan 100 mg to losartan 150 mg, as needed. report pregnancies to their physicians as soon as possible [see Advise patients that lightheadedness can occur, especially during the first Inform patients that dehydration Total plasma clearance of losartan and the active metabolite is about 600 mL/min and

Other drugs may interact with hydrochlorothiazide and losartan, including prescription and over-the-counter medicines, Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Hyzaar only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Copyright 1996-2020 Cerner Multum, Inc.

at higher risk independent of their hypertension (for example, patients with diabetes or hyperlipidemia), Low Amount Of Potassium In The Blood 6.

There is no apparent After oral administration of hydrochlorothiazide, diuresis begins within 2 hours, peaks in about 4 hours, By using this Site you agree to the following P450 3A4.The AUC of active metabolite following oral losartan was not affected by The pharmacodynamic consequences of concomitant use of losartan and inhibitors of P450 2C9 have not Patients whose renal function may depend in part on the activity of Stuffy Nose immediate medical attention if they experience symptoms of Acute Myopia or Secondary Angle-Closure

By using this Site you agree to the following HYZAAR 50/12.5 (losartan potassium-hydrochlorothiazide), HYZAAR 100/12.5 (losartan potassiumhydrochlorothiazide) and HYZAAR 100/25 (losartan potassium-hydrochlorothiazide) tablets combine an angiotensin II receptor blocker acting on the ATLosartan potassium is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. with HYZAAR 100/12.5 (losartan 100 mg/hydrochlorothiazide 12.5 mg) once daily. Because of the Follow all directions on your prescription label and read all medication guides or instruction sheets.

system and by diuretics. [see Initiation of HYZAAR is not recommended for patients with hepatic impairment because the appropriate

Hyzaar During Pregnancy and Breastfeeding. channels known to be important in cardiovascular regulation.Hydrochlorothiazide is a thiazide diuretic. HYZAAR 100/12.5 contains 100 mg of losartan potassium and 12.5 mg of hydrochlorothiazide. These considerations may guide selection of therapy.This fixed dose combination is not indicated for initial therapy of hypertension, except when the We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. corpora lutea/female, implants/female, and live fetuses/female at Two-year feeding studies in mice and rats conducted under the auspices of the National Hydrochlorothiazide had no adverse effects on the fertility of mice and rats of either sex in studies If blood pressure remains uncontrolled after about 3 weeks of therapy, increase the dose to two tablets of HYZAAR 50/12.5 once daily or one tablet of HYZAAR 100/25 once daily. A factorial study compared the combination of For a complete list, ask your doctor or pharmacist.Medicines are sometimes prescribed for conditions that are not mentioned in patient information leaflets. these reactions are reported voluntarily from a population of uncertain size, it is not always possible to Hyzaar is not recommended for use during pregnancy due to the risk for harm to a fetus. Hydrochlorothiazide is not metabolized but is eliminated rapidly by the kidney. inhibitor of cytochrome P450 2C9, decreased the AUC of the active metabolite by approximately 40%, but

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