Inactive ingredients: Inactive ingredients: colloidal silicon dioxide, crospovidone, ethylcellulose, ethylene glycol and vinyl alcohol graft copolymer, glycerol monocaprylocaprate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, talc, titanium dioxide, triethyl citrate. The dose of this medicine will be different for different patients. The adverse reaction information from clinical trials does, however, provide a basis for identifying the adverse events that appear to be related to drug use and for approximating rates.The table below lists adverse reactions in the MERIT-HF study that occurred at an incidence of ≥ 1% in the Metoprolol Succinate Extended-Release Tablets group and greater than placebo by more than 0.5%, regardless of the assessment of causality.The following adverse reactions have been identified during post-approval use of Metoprolol Succinate Extended-Release Tablets or immediate-release metoprolol. 25 mg PO qDay initially; increased every 2 weeks PRN; target dosage, 200 mg/day Metoprolol IV Dosing 5 mg over 2 mins, every 5 mins for up to total 15 mg Metoprolol IV Conversion to PO dosing Can start 1st oral dose within 20 mins of initial IV to estimate dosing needs.
BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER. These increases in plasma concentration would decrease the cardioselectivity of metoprolol.Digitalis glycosides, clonidine, diltiazem and verapamil slow atrioventricular conduction and decrease heart rate.
Applies to the following strengths: 1 mg/mL; 50 mg; 100 mg; 25 mg; 200 mg; 37.5 mg; 75 mg; 10 mg/mLInitiate at low doses and titrate gradually according to clinical response.For treatment of hypertension and angina, when switching from immediate release to extended release, use the same total daily dose.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
Retain in carton until time of use.The authors make no claims of the accuracy of the information contained herein; and these suggested doses and/or guidelines are not a substitute for clinical judgment. It's a drug called a beta-blocker. May switch to oral dosing (50 to 100mg po q6h) after IV bolus therapy. During the intravenous administration of metoprolol tartrate, blood pressure, heart rate, and electrocardiogram should be carefully monitored. Available for Android and iOS devices. Patients were stabilized on optimal concomitant therapy for heart failure, including diuretics, ACE inhibitors, cardiac glycosides, and nitrates. Nonetheless, subgroup analyses can be difficult to interpret and it is not known whether these represent true differences or chance effects.1. The protocol excluded patients with contraindications to beta-blocker use, those expected to undergo heart surgery, and those within 28 days of myocardial infarction or unstable angina. Therefore, initiate therapy at doses lower than those recommended for a given indication; and increase doses gradually in patients with impaired hepatic function.The systemic availability and half-life of metoprolol in patients with renal failure do not differ to a clinically significant degree from those in normal subjects. Patients with myocardial infarction or heart failure may be prone to significant hemodynamic instability. In patients who tolerate full 15 mg dose, oral lopressor 50mg po q6h should be started 15 min after last IV dose x 48 hours. If these are tolerated, give 50 mg PO 15 min after the last IV dose and q 6 hr for 48 hr. When discontinuing chronically administered Metoprolol Succinate Extended-Release Tablets, particularly in patients with ischemic heart disease, the dosage should be gradually reduced over a period of 1 to 2 weeks and the patient should be carefully monitored. Total 5 mg IV→ start 12.5 mg PO Q6H Total 10 mg IV→ start 2 5mg PO Q6H Total 15 mg IV→ start 37.5 mg PO Q6H If at 50mg q6 and HR >110, consider adding diltiazem.
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